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The role of thoracic duct lymph in gastrin transport and gastric secretion
  1. B. Guy Clendinnen,
  2. David D. Reeder,
  3. James C. Thompson


    The effect of thoracic lymph diversion on gastric secretion has been studied in dogs. In addition, the concentration of gastrin in thoracic duct lymph of nine dogs and two patients has been measured before and during antral stimulation with either food or acetylcholine. The secretory studies do not support the concept that there is a significant gastric secretagogue in thoracic duct lymph. The amount of gastrin carried in thoracic duct lymph as determined by radioimmunoassay is far less than that necessary to evoke a gastric secretory response.

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    • 1 Supported by grants from the National Institutes of Health, AM 15241, and General Clinical Research Centers Branch, RR-00073, and by a grant from the John A. Hartford Foundation, Inc.