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Carbohydrate content of endoscopic gastric biopsies in carcinoma of the stomach.
  1. G Machado,
  2. J R Clamp,
  3. A E Read


    An investigation of the glycoproteins of gastric mucus from biopsies of patients with gastric cancer has shown a change in certain carbohydrate components. There is a significant increase (P less than 0-001) in mannose and a significant decrease in N-acetylgalactosamine in both secretors and non-secretors from cancer-free and cancer-bearing regions of the stomach as compared with normal stomachs. The possible reasons for this change and its relation to two possible glycoprotein fractions are discussed.

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