Article Text

Download PDFPDF
Effects of [Asu1,7]-eel calcitonin on gastric somatostatin and gastrin release.
  1. T Chiba,
  2. T Taminato,
  3. S Kadowaki,
  4. Y Goto,
  5. K Mori,
  6. Y Seino,
  7. H Abe,
  8. K Chihara,
  9. S Matsukura,
  10. T Fujita,
  11. T Kondo


    Effects of [Asu1,7]-eel calcitonin on gastric somatostatin and gastrin secretion were studied by using the isolated perfused rat stomach. [Asu1,7]-eel calcitonin (10(-9)--10(-7)M) caused a simultaneous dose-dependent increase of gastric somatostatin release and decrease of gastrin secretion, with a significant correlation between these two. The demonstration of calcitonin stimulation of gastric somatostatin release raises the possibility of somatostatin-mediated suppression of gastrin secretion by calcitonin.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.