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Impaired acetaldehyde oxidation in alcoholics
  1. K R Palmer,
  2. W J Jenkins

    Abstract

    High blood acetaldehyde levels in alcoholics after ethanol ingestion are due to reduced acetaldehyde oxidation rather than to an increased rate of its formation from ethanol. This is associated with low hepatic acetaldehyde dehydrogenase activity in alcoholic subjects and may represent a specific abnormality in them.

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    Footnotes

    • * Presented in part to the British Society of Gastroenterology Meeting, Bristol 1981.