Article Text


CCK-related peptides stimulation of the Na+/H+ antiport in pancreatic acinar cells leads to cytoplasmic alkalinisation.
  1. M J Bastie,
  2. M Dufresne,
  3. M Delvaux,
  4. N Vaysse,
  5. A Ribet
  1. U151 INSERM, CHU Rangueil, Toulouse, France.


    Caerulein, gastrin and pentagastrin stimulation of the Na+/H+ exchange leads to intracellular alkalinisation in pancreatic acinar cells. Activation of protein kinase-C is the more probable mechanism involved in the effect of caerulein.

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