Article Text

Download PDFPDF

Is a persistent adenovirus infection involved in coeliac disease?
  1. M J Carter,
  2. M M Willcocks,
  3. H C Mitchison,
  4. C O Record,
  5. C R Madeley
  1. Department of Virology, University of Newcastle-upon-Tyne.


    Recent evidence has implicated adenovirus 12 in the aetiology of coeliac disease so that persistent infection by this virus must be considered. We have undertaken a search for adenovirus DNA in duodenal biopsy samples from a total of 26 coeliac and non-coeliac patients. We could find no evidence of persistent virus DNA by Southern blot techniques even under conditions which approach a sensitivity of one copy of virus genome per cell, and use either adenovirus 12 or 41 DNA.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.