Article Text

Download PDFPDF

Effect of glucocorticoid on liver regeneration after partial hepatectomy in the rat.
  1. I Tsukamoto,
  2. S Kojo
  1. Department of Food Science and Nutrition, Nara Women's University, Japan.


    The increase in activities of hepatic thymidylate synthetase (EC and thymidine kinase (EC, which catalyse the formation of thymidylate through the de novo and salvage pathways, respectively, were significantly suppressed during liver regeneration in rats which were given glucocorticoids (hydrocortisone and dexamethasone) or indomethacin. These drugs also prevented the augment of hepatic DNA content in 24 h regenerating liver.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.