Article Text

Download PDFPDF

Abolition by omeprazole of aspirin induced gastric mucosal injury in man.
  1. T K Daneshmend,
  2. A G Stein,
  3. N K Bhaskar,
  4. C J Hawkey
  1. University Department of Therapeutics, University Hospital, Nottingham.


    This study investigates whether aspirin injury to the human gastric mucosa can be prevented by profound acid suppression with omeprazole, in a randomised, double blind, crossover design according to latin square. It was concluded that profound acid suppression can prevent aspirin induced gastric mucosal injury in normal subjects. This approach may prevent the development of peptic ulcers and their complications in patients taking aspirin and other non-steroidal anti-inflammatory drugs.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.