Article Text

Download PDFPDF
Colorectal cancer in ulcerative colitis. Influence of anatomical extent and age at onset on colitis-cancer interval.
  1. A Sugita,
  2. D B Sachar,
  3. C Bodian,
  4. M B Ribeiro,
  5. A H Aufses, Jr,
  6. A J Greenstein
  1. Department of Surgery, Mount Sinai School of Medicine, City University of New York, New York.

    Abstract

    We have examined the age at onset of both ulcerative colitis and colitis-associated colorectal cancer in 100 patients seen at Mount Sinai Hospital between 1959 and 1988. There were 85 patients with extensive colitis and 15 with left sided colitis. There was a strong direct correlation between the age at onset of ulcerative colitis and age at diagnosis of cancer (p less than 0.0001); this correlation was found both in patients with extensive colitis (p less than 0.0001) and in those with left sided colitis (p less than 0.005). Patients with left sided colitis developed both their colitis and their cancers about a decade later than did those with extensive disease, but the mean duration of colitis before diagnosis of cancer was virtually the same (about 21 years) in both groups, irrespective of the age at onset of disease.

    Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.