An antibody precipitating urease was found in 171 out of 180 human sera. Data obtained on limited material (50 cases) suggest that the anti-urease titre is appreciably higher in the serum of patients suffering from gastric ulcer. This is a pointer towards a possible antigen-antibody mechanism in the genesis of chronic gastric ulceration.
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↵1 This is a preliminary communication based on work begun at the Institute of Clinical Research, Middlesex Hospital Medical School, where it was supported by a Leverhulme research scholarship and formed the basis of a Ph.D. thesis (London, 1961).
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