Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 during intestinal inflammation

S Nikolaus; J Bauditz; P Gionchetti; C Witt; H Lochs; S Schreiber

doi:10.1136/gut.42.4.470

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Inflammation and inflammatory bowel disease

Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 during intestinal inflammation

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Online download statistics by month: January 1999 to March 2024

	Abstract	Full	Pdf
Jan 1999	7	12	5
Feb 1999	5	8	18
Mar 1999	3	12	7
Apr 1999	4	21	5
May 1999	0	11	10
Jun 1999	1	7	8
Jul 1999	2	11	10
Aug 1999	4	11	6
Sep 1999	3	4	4
Oct 1999	8	17	19
Nov 1999	1	10	3
Dec 1999	2	4	4
Jan 2000	0	7	9
Feb 2000	1	1	4
Mar 2000	2	5	6
Apr 2000	1	5	2
May 2000	2	6	6
Jun 2000	1	3	1
Jul 2000	0	1	1
Aug 2000	1	8	2
Sep 2000	1	13	3
Oct 2000	2	8	4
Nov 2000	3	1	3
Dec 2000	0	5	10
Jan 2001	1	17	4
Feb 2001	0	9	12
Mar 2001	1	12	9
Apr 2001	2	4	8
May 2001	4	8	0
Jun 2001	0	6	11
Jul 2001	0	6	3
Aug 2001	2	6	2
Sep 2001	2	20	4
Oct 2001	1	11	7
Nov 2001	1	5	2
Dec 2001	0	5	2
Jan 2002	3	10	8
Feb 2002	7	11	5
Mar 2002	4	3	1
Apr 2002	5	8	2
May 2002	1	6	4
Jun 2002	6	7	2
Jul 2002	1	7	3
Aug 2002	2	7	3
Sep 2002	1	4	6
Oct 2002	0	4	7
Nov 2002	0	5	5
Dec 2002	2	10	3
Jan 2003	2	5	3
Feb 2003	0	7	11
Mar 2003	2	9	9
Apr 2003	1	3	2
May 2003	1	7	3
Jun 2003	4	5	4
Jul 2003	5	18	2
Aug 2003	15	19	2
Sep 2003	12	6	6
Oct 2003	14	26	2
Nov 2003	20	13	6
Dec 2003	12	10	1
Jan 2004	13	13	4
Feb 2004	14	9	3
Mar 2004	11	9	11
Apr 2004	14	15	6
May 2004	10	14	3
Jun 2004	23	17	7
Jul 2004	26	29	7
Aug 2004	13	18	19
Sep 2004	6	9	9
Oct 2004	6	37	13
Nov 2004	5	38	6
Dec 2004	10	42	8
Jan 2005	12	46	16
Feb 2005	10	31	11
Mar 2005	11	35	10
Apr 2005	3	16	12
May 2005	7	16	8
Jun 2005	6	17	7
Jul 2005	5	33	14
Aug 2005	7	16	7
Sep 2005	10	16	10
Oct 2005	17	47	34
Nov 2005	19	24	8
Dec 2005	11	18	15
Jan 2006	6	24	13
Feb 2006	5	19	6
Mar 2006	6	20	15
Apr 2006	4	22	5
May 2006	13	21	13
Jun 2006	9	19	9
Jul 2006	4	13	6
Aug 2006	9	9	3
Sep 2006	15	19	12
Oct 2006	12	22	8
Nov 2006	14	19	10
Dec 2006	8	13	10
Jan 2007	19	17	14
Feb 2007	10	10	8
Mar 2007	13	16	15
Apr 2007	16	5	2
May 2007	8	6	3
Jun 2007	8	4	7
Jul 2007	11	7	7
Aug 2007	12	5	5
Sep 2007	16	8	5
Oct 2007	20	3	5
Nov 2007	7	5	4
Dec 2007	3	4	2
Jan 2008	12	0	5
Feb 2008	13	10	5
Mar 2008	20	3	5
Apr 2008	38	2	5
May 2008	1	3	1
Jun 2008	7	3	3
Jul 2008	14	7	3
Aug 2008	35	2	1
Sep 2008	15	5	8
Oct 2008	9	3	1
Nov 2008	9	5	4
Dec 2008	11	7	6
Jan 2009	9	0	2
Feb 2009	6	2	1
Mar 2009	7	5	3
Apr 2009	9	4	5
May 2009	7	4	2
Jun 2009	6	4	1
Jul 2009	8	4	1
Aug 2009	11	1	3
Sep 2009	9	4	1
Oct 2009	17	2	0
Nov 2009	7	8	8
Dec 2009	5	2	2
Jan 2010	8	5	5
Feb 2010	11	4	1
Mar 2010	12	4	1
Apr 2010	24	8	5
May 2010	20	15	6
Jun 2010	25	7	6
Jul 2010	13	6	7
Aug 2010	10	6	2
Sep 2010	12	4	3
Oct 2010	26	11	1
Nov 2010	19	5	1
Dec 2010	18	3	2
Jan 2011	4	3	4
Feb 2011	13	7	8
Mar 2011	18	2	1
Apr 2011	8	6	3
May 2011	6	2	1
Jun 2011	13	2	2
Jul 2011	18	2	1
Aug 2011	15	5	1
Sep 2011	19	5	4
Oct 2011	20	5	2
Nov 2011	27	13	5
Dec 2011	12	26	6
Jan 2012	16	16	7
Feb 2012	11	18	3
Mar 2012	10	12	8
Apr 2012	10	17	11
May 2012	15	21	10
Jun 2012	22	21	13
Jul 2012	11	21	6
Aug 2012	17	19	7
Sep 2012	10	21	8
Oct 2012	16	21	12
Nov 2012	8	27	9
Dec 2012	13	17	11
Jan 2013	9	14	9
Feb 2013	18	21	3
Mar 2013	8	16	9
Apr 2013	11	11	12
May 2013	9	17	10
Jun 2013	16	24	6
Jul 2013	14	10	6
Aug 2013	14	5	9
Sep 2013	5	2	2
Oct 2013	10	13	4
Nov 2013	8	13	10
Dec 2013	8	7	7
Jan 2014	13	13	4
Feb 2014	5	9	5
Mar 2014	5	17	10
Apr 2014	7	11	9
May 2014	10	33	5
Jun 2014	5	17	5
Jul 2014	18	36	4
Aug 2014	15	58	6
Sep 2014	5	65	5
Oct 2014	4	151	4
Nov 2014	4	107	1
Dec 2014	16	29	5
Jan 2015	16	34	4
Feb 2015	3	15	10
Mar 2015	9	17	14
Apr 2015	1	13	5
May 2015	7	19	10
Jun 2015	3	17	5
Jul 2015	4	22	4
Aug 2015	10	9	1
Sep 2015	16	15	1
Oct 2015	6	11	0
Nov 2015	12	11	5
Dec 2015	18	9	2
Jan 2016	9	16	8
Feb 2016	14	8	0
Mar 2016	16	4	10
Apr 2016	7	9	4
May 2016	3	9	9
Jun 2016	13	5	9
Jul 2016	8	10	7
Aug 2016	16	4	8
Sep 2016	10	6	6
Oct 2016	11	6	9
Nov 2016	5	12	1
Dec 2016	5	13	3
Jan 2017	17	11	6
Feb 2017	4	11	2
Mar 2017	4	7	4
Apr 2017	8	13	0
May 2017	7	13	12
Jun 2017	7	13	3
Jul 2017	24	23	4
Aug 2017	21	21	1
Sep 2017	18	18	2
Oct 2017	32	24	2
Nov 2017	28	22	6
Dec 2017	18	20	2
Jan 2018	31	21	6
Feb 2018	23	10	8
Mar 2018	14	12	2
Apr 2018	27	23	6
May 2018	31	31	6
Jun 2018	34	34	1
Jul 2018	24	22	4
Aug 2018	35	33	7
Sep 2018	27	23	4
Oct 2018	42	40	8
Nov 2018	52	48	13
Dec 2018	29	29	6
Jan 2019	32	30	4
Feb 2019	49	48	9
Mar 2019	37	38	17
Apr 2019	39	39	13
May 2019	58	53	11
Jun 2019	40	40	6
Jul 2019	40	36	13
Aug 2019	32	26	6
Sep 2019	37	34	8
Oct 2019	39	37	7
Nov 2019	45	33	7
Dec 2019	51	37	3
Jan 2020	70	53	7
Feb 2020	34	28	3
Mar 2020	38	34	10
Apr 2020	40	36	10
May 2020	42	36	9
Jun 2020	39	39	11
Jul 2020	40	38	5
Aug 2020	35	29	5
Sep 2020	58	52	19
Oct 2020	52	50	3
Nov 2020	65	56	8
Dec 2020	63	53	11
Jan 2021	54	48	9
Feb 2021	33	29	7
Mar 2021	59	47	14
Apr 2021	60	48	8
May 2021	34	30	10
Jun 2021	30	30	2
Jul 2021	36	33	34
Aug 2021	29	29	16
Sep 2021	31	31	12
Oct 2021	27	26	20
Nov 2021	27	22	29
Dec 2021	35	31	13
Jan 2022	34	35	7
Feb 2022	30	27	22
Mar 2022	28	23	11
Apr 2022	29	25	9
May 2022	40	37	29
Jun 2022	42	27	9
Jul 2022	31	21	4
Aug 2022	25	25	2
Sep 2022	26	22	12
Oct 2022	54	53	17
Nov 2022	48	44	8
Dec 2022	45	41	7
Jan 2023	31	31	10
Feb 2023	60	52	7
Mar 2023	30	28	11
Apr 2023	13	11	9
May 2023	19	14	9
Jun 2023	15	11	7
Jul 2023	20	8	6
Aug 2023	13	10	32
Sep 2023	27	15	11
Oct 2023	34	30	9
Nov 2023	14	14	1
Dec 2023	69	8	3
Jan 2024	28	2	1
Feb 2024	69	4	1
Mar 2024	91	0	0
Total	5031	5354	2041

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