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Helicobacter pylori: beware “blind” eradication!
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  1. C D ROSEVEARE,
  2. D A VAN HEEL,
  3. M J P ARTHUR
  1. R J LAWRANCE
  1. Department of Medicine,
  2. Southampton University Hospitals NHS Trust,
  3. Tremona Road,
  4. Southampton SO9 4XY, UK
  5. Department of Surgery
  1. Dr Roseveare, Specialist Registrar in Medicine/Gastroenterology, Queen Alexandra Hospital, Portsmouth PO6 3LY, UK.

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Editor,—The Maastricht Consensus Report (Gut1997;41:8–13) has recommended broadening the guidelines on eradication of Helicobacter pylori to include certain dyspeptic patients without confirmed peptic ulceration. Although this policy may improve dyspeptic symptoms in certain subgroups of patients without ulcers,1 an overall benefit from eradication of H pylori in non-ulcer dyspepsia has yet to be established. Furthermore, while a “test and treat” strategy may have cost benefits,2 potential dangers to individual patients should be considered. Such dangers are illustrated by a patient who was recently admitted under our care with fulminant pseudomembranous colitis following triple therapy for the treatment ofH pylori.

The 40 year old woman …

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