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Iron reduction therapy in hepatitis C
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  1. Y LURIE,
  2. M BEER GABEL,
  3. I LAMBORT,
  4. T SOUMATZKY,
  5. S D H MALNICK,
  6. D D BASS
  1. Kaplan Medical Center, Affiliated to the
  2. Hebrew University Medical School and Hadassah,
  3. PO Box 1, Rehovot 76100, Israel

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Editor,—Three papers in the July issue report on the possible association between iron and tissue damage in conditions other than haemochromatosis. Tan et al (Gut1997;41:14–18) found that gastric cancer cells are more susceptible to photodynamic therapy when iron is removed. Boucheret al (Gut 1997;41:115–20) found that treatment of hepatitis C with interferon leads to a decrease in liver iron content. Bacon (Gut1997;41:127–8) briefly commented on the association between iron and hepatitis C, including some evidence that iron depletion may be beneficial in patients who fail to respond to interferon α.

Shortly after Bacon et al’s pioneering report in 1993 on iron …

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