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Stomach
Gastric involvement in AIDS associated cryptosporidiosis
  1. P Rossia,
  2. F Rivasib,
  3. M Codeluppic,
  4. A Cataniac,
  5. A Tamburrinia,
  6. E Righib,
  7. E Pozioa
  1. aLaboratory of Parasitology, Istituto Superiore di Sanità, Rome, Italy, bDepartment of Morphological Sciences and Forensic Medicine, cDepartment of Infectious Diseases, University of Modena, Modena, Italy
  1. Dr E Pozio, Laboratory of Parasitology, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

Abstract

Background—Cryptosporidiosis has been shown to be a common cause of diarrhoea in both immunocompetent and immunosuppressed individuals. There are very few data on the distribution of Cryptosporidium parvumalong the gastrointestinal tract.

Aims—To evaluate the location ofCryptosporidium parasites in the digestive tract of patients with AIDS.

Methods—Gastrointestinal localisation ofC parvum was studied in 71 patients with AIDS who underwent upper and/or lower endoscopy with biopsy for chronic diarrhoeal illness and/or other gastrointestinal disorders of unexplained origin.

Results—Twenty four individuals (33.8%) were positive for C parvum, of which 16 (88.9%) had parasites in the gastric epithelium. Most patients with gastric localisation of C parvum did not show specific symptoms indicating the presence of this parasite in the stomach.

Conclusions—Gastric involvement in AIDS related cryptosporidiosis is more frequent than expected, but no clear correlation between gastric location and related clinical and pathological features was observed.

  • Cryptosporidium parvum
  • AIDS
  • gastric location

https://doi.org/10.1136/gut.43.4.476

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