Article Text

Cost effectiveness of treatment for gastro-oesophageal reflux
  1. R J F LAHEIJ,
  2. J B M J JANSEN
  1. J L SEVERENS
  1. A L M VERBEEK
  1. Department of Gastroenterology,
  2. University Hospital Nijmegen,
  3. Nijmegen, The Netherlands
  4. Department of Medical Technology Assessment,
  5. University of Nijmegen,
  6. Nijmegen, The Netherlands
  7. Department of Epidemiology,
  8. University of Nijmegen,
  9. Nijmegen, The Netherlands
  1. Dr Laheij, MIES (152), PO Box 9101, 6500 HB Nijmegen, The Netherlands (email: R.Laheij{at}mie.kun.nl).

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Editor,—Eggleston et al(Gut 1998;42:13–16) concluded from their observational study that the “step up” approach, starting with a prokinetic or H2 receptor antagonist, represents the most cost effective initial therapeutic strategy for the treatment of patients with a diagnosis of uncomplicated gastro-oesophageal reflux disease (GORD). In studies of the effects of treatments, non-randomised comparisons can be affected by confounding factors1 and in our opinion this has resulted in the wrong conclusions being drawn from this study. Therapeutic interventions are commonly prompted by an indication. Primary care physicians selectively treat patients exhibiting more severe GORD with omeprazole and less severe symptoms …

View Full Text