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Gallstones: an intestinal disease?
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  1. K J VAN ERPECUM,
  2. G P VAN BERGE-HENEGOUWEN
  1. Department of Gastroenterology, University Hospital Utrecht,
  2. Postbox 85500, 3508GA Utrecht, The Netherlands
  1. Dr van Erpecum.

Abstract

Current evidence suggests that impaired intestinal motility may facilitate gallstone formation by influencing biliary deoxycholate levels or by modulating interdigestive gall bladder motility (fig 2), although a primary intestinal defect in gallstone pathogenesis has not yet been demonstrated. In the cold war period, most interesting events, from a political point of view, occurred at the border between capitalist and communist systems, near the iron curtain. Similarly, the gall bladder and biliary tract can be viewed as the border between liver and intestinal tract, where many interesting things occur with profound impact on both systems. Combined efforts by researchers in the field of hepatology and gastrointestinal motility should brake down the Berlin wall of ignorance of one of the most common diseases in the Western world.

  • Abbreviations

    CCK
    cholecystokinin
    MMC
    migrating motor complex
  • Statistics from Altmetric.com

  • Abbreviations

    CCK
    cholecystokinin
    MMC
    migrating motor complex
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