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Bile acids are physiological ligands for a nuclear receptor
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* See also Parks DJ, Blanchard SG, Bledsoe RK, et al. Bile acids: natural ligands for an orphan receptor.Science1999;284:1365–8; and Wang H, Chen J, Hollister K, et al. Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol Cell 1999;3:543–53.