The 5-HT3 receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinalc-fos expression in the anaesthetised rat

C M Kozlowski; A Green; D Grundy; F M Boissonade; C Bountra

doi:10.1136/gut.46.4.474

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The 5-HT₃ receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinalc-fos expression in the anaesthetised rat

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Online download statistics by month: March 2000 to March 2024

	Abstract	Full	Pdf
Mar 2000	70	98	41
Apr 2000	27	74	26
May 2000	10	30	27
Jun 2000	4	17	18
Jul 2000	12	23	11
Aug 2000	1	18	14
Sep 2000	4	16	22
Oct 2000	2	12	11
Nov 2000	0	13	5
Dec 2000	1	9	9
Jan 2001	1	6	1
Feb 2001	4	6	6
Mar 2001	1	8	5
Apr 2001	8	15	8
May 2001	4	17	8
Jun 2001	1	3	2
Jul 2001	1	19	16
Aug 2001	4	6	6
Sep 2001	2	4	0
Oct 2001	0	6	9
Nov 2001	1	6	3
Dec 2001	2	8	1
Jan 2002	1	6	10
Feb 2002	1	1	0
Mar 2002	2	14	7
Apr 2002	1	9	2
May 2002	2	5	1
Jun 2002	0	8	6
Jul 2002	1	6	6
Aug 2002	1	3	0
Sep 2002	1	9	4
Oct 2002	1	7	7
Nov 2002	0	5	1
Dec 2002	3	5	1
Jan 2003	1	7	4
Feb 2003	4	10	13
Mar 2003	1	5	8
Apr 2003	3	8	6
May 2003	4	3	1
Jun 2003	1	8	6
Jul 2003	11	14	7
Aug 2003	16	11	9
Sep 2003	10	9	2
Oct 2003	15	9	9
Nov 2003	24	14	4
Dec 2003	13	10	4
Jan 2004	15	7	1
Feb 2004	17	11	3
Mar 2004	18	19	9
Apr 2004	21	17	12
May 2004	36	37	7
Jun 2004	39	42	3
Jul 2004	46	53	8
Aug 2004	29	32	3
Sep 2004	22	46	23
Oct 2004	10	40	12
Nov 2004	10	38	16
Dec 2004	12	33	11
Jan 2005	8	48	16
Feb 2005	6	25	10
Mar 2005	20	29	14
Apr 2005	2	10	11
May 2005	3	28	22
Jun 2005	6	19	14
Jul 2005	7	19	6
Aug 2005	4	17	7
Sep 2005	8	11	9
Oct 2005	7	9	5
Nov 2005	5	14	13
Dec 2005	7	4	7
Jan 2006	5	15	11
Feb 2006	4	12	9
Mar 2006	5	17	7
Apr 2006	7	13	4
May 2006	5	9	3
Jun 2006	3	10	6
Jul 2006	4	6	3
Aug 2006	6	13	8
Sep 2006	1	5	5
Oct 2006	11	16	7
Nov 2006	5	13	5
Dec 2006	6	10	6
Jan 2007	10	12	7
Feb 2007	13	16	8
Mar 2007	10	13	9
Apr 2007	8	3	3
May 2007	6	3	3
Jun 2007	7	7	7
Jul 2007	5	4	5
Aug 2007	8	7	4
Sep 2007	7	6	1
Oct 2007	6	7	2
Nov 2007	3	6	4
Dec 2007	7	2	4
Jan 2008	7	3	6
Feb 2008	9	6	4
Mar 2008	11	2	3
Apr 2008	12	2	7
May 2008	2	3	0
Jun 2008	14	3	0
Jul 2008	8	2	2
Aug 2008	19	5	4
Sep 2008	7	0	0
Oct 2008	10	2	1
Nov 2008	14	2	3
Dec 2008	11	1	1
Jan 2009	9	2	2
Feb 2009	8	0	1
Mar 2009	14	6	4
Apr 2009	13	1	0
May 2009	5	1	1
Jun 2009	16	2	6
Jul 2009	9	2	1
Aug 2009	8	0	1
Sep 2009	10	1	0
Oct 2009	19	2	1
Nov 2009	10	2	4
Dec 2009	5	0	0
Jan 2010	20	0	4
Feb 2010	5	1	1
Mar 2010	6	2	4
Apr 2010	7	5	2
May 2010	9	4	1
Jun 2010	17	0	3
Jul 2010	3	4	6
Aug 2010	14	1	1
Sep 2010	20	4	0
Oct 2010	11	15	2
Nov 2010	8	7	0
Dec 2010	9	1	0
Jan 2011	11	6	3
Feb 2011	10	5	1
Mar 2011	12	6	0
Apr 2011	13	0	1
May 2011	10	3	2
Jun 2011	8	1	0
Jul 2011	13	1	5
Aug 2011	7	6	1
Sep 2011	9	3	1
Oct 2011	10	4	2
Nov 2011	10	8	3
Dec 2011	4	11	4
Jan 2012	11	13	6
Feb 2012	5	20	1
Mar 2012	8	8	9
Apr 2012	4	8	14
May 2012	10	14	7
Jun 2012	10	10	5
Jul 2012	10	7	11
Aug 2012	7	6	6
Sep 2012	6	9	2
Oct 2012	15	15	12
Nov 2012	13	12	5
Dec 2012	20	6	5
Jan 2013	14	8	13
Feb 2013	10	17	11
Mar 2013	9	12	6
Apr 2013	9	8	7
May 2013	11	10	8
Jun 2013	2	5	5
Jul 2013	6	6	6
Aug 2013	13	3	3
Sep 2013	12	19	12
Oct 2013	2	4	3
Nov 2013	15	5	7
Dec 2013	5	7	5
Jan 2014	6	6	10
Feb 2014	5	5	6
Mar 2014	10	10	9
Apr 2014	8	9	7
May 2014	16	11	5
Jun 2014	10	2	4
Jul 2014	19	9	0
Aug 2014	3	6	2
Sep 2014	6	5	4
Oct 2014	3	6	6
Nov 2014	7	10	7
Dec 2014	6	5	4
Jan 2015	4	5	3
Feb 2015	5	4	4
Mar 2015	9	7	3
Apr 2015	2	4	5
May 2015	12	8	5
Jun 2015	10	4	4
Jul 2015	8	8	7
Aug 2015	12	6	3
Sep 2015	10	4	4
Oct 2015	5	4	9
Nov 2015	7	5	3
Dec 2015	18	7	5
Jan 2016	13	0	2
Feb 2016	5	6	6
Mar 2016	12	8	5
Apr 2016	6	3	4
May 2016	13	2	4
Jun 2016	3	7	4
Jul 2016	9	10	2
Aug 2016	3	4	5
Sep 2016	7	1	6
Oct 2016	18	2	6
Nov 2016	12	2	2
Dec 2016	10	5	1
Jan 2017	8	4	2
Feb 2017	6	4	4
Mar 2017	3	12	3
Apr 2017	1	22	0
May 2017	3	26	6
Jun 2017	7	14	1
Jul 2017	6	6	3
Aug 2017	16	16	1
Sep 2017	18	16	0
Oct 2017	11	11	5
Nov 2017	20	20	1
Dec 2017	18	18	0
Jan 2018	29	25	5
Feb 2018	10	10	2
Mar 2018	8	8	6
Apr 2018	15	13	6
May 2018	21	16	3
Jun 2018	24	22	1
Jul 2018	11	11	0
Aug 2018	5	5	2
Sep 2018	9	9	3
Oct 2018	12	12	1
Nov 2018	25	25	5
Dec 2018	16	16	5
Jan 2019	9	9	2
Feb 2019	8	6	0
Mar 2019	9	9	6
Apr 2019	10	10	9
May 2019	8	8	5
Jun 2019	6	4	3
Jul 2019	14	13	19
Aug 2019	17	12	4
Sep 2019	9	7	4
Oct 2019	21	21	10
Nov 2019	11	9	5
Dec 2019	24	18	2
Jan 2020	14	14	4
Feb 2020	16	13	5
Mar 2020	11	8	3
Apr 2020	11	6	9
May 2020	4	4	5
Jun 2020	12	8	4
Jul 2020	16	14	12
Aug 2020	7	7	5
Sep 2020	23	20	3
Oct 2020	19	19	6
Nov 2020	9	9	3
Dec 2020	13	13	12
Jan 2021	16	12	7
Feb 2021	15	9	1
Mar 2021	6	6	2
Apr 2021	5	5	4
May 2021	10	8	5
Jun 2021	9	9	3
Jul 2021	10	10	9
Aug 2021	6	6	11
Sep 2021	8	7	4
Oct 2021	17	11	16
Nov 2021	9	5	13
Dec 2021	18	12	9
Jan 2022	15	14	3
Feb 2022	27	21	7
Mar 2022	28	24	4
Apr 2022	23	21	4
May 2022	35	29	18
Jun 2022	33	31	5
Jul 2022	20	20	1
Aug 2022	24	24	6
Sep 2022	39	29	14
Oct 2022	69	63	13
Nov 2022	35	31	8
Dec 2022	42	34	4
Jan 2023	25	23	8
Feb 2023	36	36	2
Mar 2023	20	17	3
Apr 2023	6	6	2
May 2023	7	5	8
Jun 2023	11	5	0
Jul 2023	28	10	8
Aug 2023	5	4	4
Sep 2023	27	13	6
Oct 2023	17	17	6
Nov 2023	45	45	2
Dec 2023	151	16	1
Jan 2024	27	5	0
Feb 2024	57	2	1
Mar 2024	99	4	2
Total	3505	3264	1603

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