Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor α in a human colonic cell line

A Banan; Y Zhang; J Losurdo; A Keshavarzian

doi:10.1136/gut.46.6.830

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Cell biology

Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor α in a human colonic cell line

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Online download statistics by month: May 2000 to March 2024

	Abstract	Full	Pdf
May 2000	21	23	14
Jun 2000	22	26	10
Jul 2000	6	23	13
Aug 2000	3	18	18
Sep 2000	1	6	3
Oct 2000	4	5	2
Nov 2000	1	3	1
Dec 2000	0	6	5
Jan 2001	0	4	4
Feb 2001	1	3	2
Mar 2001	2	3	3
Apr 2001	4	10	4
May 2001	2	5	3
Jun 2001	1	4	2
Jul 2001	1	10	3
Aug 2001	2	7	3
Sep 2001	0	6	6
Oct 2001	2	6	0
Nov 2001	1	5	2
Dec 2001	2	8	2
Jan 2002	4	13	1
Feb 2002	0	9	1
Mar 2002	1	8	1
Apr 2002	1	2	0
May 2002	2	10	8
Jun 2002	0	7	1
Jul 2002	0	2	4
Aug 2002	0	3	5
Sep 2002	1	3	3
Oct 2002	3	13	3
Nov 2002	0	6	3
Dec 2002	3	3	1
Jan 2003	1	7	1
Feb 2003	1	8	4
Mar 2003	3	12	4
Apr 2003	1	2	0
May 2003	5	3	3
Jun 2003	4	11	1
Jul 2003	13	20	0
Aug 2003	17	11	5
Sep 2003	24	10	1
Oct 2003	19	14	2
Nov 2003	40	6	1
Dec 2003	54	18	8
Jan 2004	61	12	2
Feb 2004	61	9	2
Mar 2004	66	17	1
Apr 2004	24	12	7
May 2004	70	36	9
Jun 2004	75	46	3
Jul 2004	93	55	6
Aug 2004	41	47	5
Sep 2004	58	54	4
Oct 2004	32	30	15
Nov 2004	41	31	5
Dec 2004	40	29	4
Jan 2005	33	34	16
Feb 2005	24	32	8
Mar 2005	26	25	12
Apr 2005	16	9	13
May 2005	16	31	8
Jun 2005	16	40	10
Jul 2005	10	13	2
Aug 2005	16	17	5
Sep 2005	12	13	4
Oct 2005	14	19	6
Nov 2005	17	14	7
Dec 2005	11	17	7
Jan 2006	12	28	10
Feb 2006	10	22	9
Mar 2006	8	13	4
Apr 2006	9	9	8
May 2006	7	16	8
Jun 2006	14	9	11
Jul 2006	8	14	10
Aug 2006	6	4	3
Sep 2006	9	16	6
Oct 2006	10	23	9
Nov 2006	9	20	12
Dec 2006	10	15	8
Jan 2007	8	5	6
Feb 2007	7	7	5
Mar 2007	6	17	13
Apr 2007	14	7	7
May 2007	8	3	7
Jun 2007	8	2	2
Jul 2007	8	1	0
Aug 2007	6	5	2
Sep 2007	7	4	2
Oct 2007	12	2	2
Nov 2007	4	7	6
Dec 2007	4	1	1
Jan 2008	6	5	3
Feb 2008	16	7	7
Mar 2008	19	13	5
Apr 2008	10	6	3
May 2008	13	1	2
Jun 2008	5	2	3
Jul 2008	9	7	8
Aug 2008	29	3	2
Sep 2008	20	7	0
Oct 2008	26	8	6
Nov 2008	10	5	2
Dec 2008	3	4	4
Jan 2009	6	2	1
Feb 2009	7	4	5
Mar 2009	24	5	3
Apr 2009	12	15	6
May 2009	10	5	4
Jun 2009	14	4	7
Jul 2009	10	5	3
Aug 2009	9	2	2
Sep 2009	7	4	5
Oct 2009	14	1	0
Nov 2009	11	1	1
Dec 2009	7	3	0
Jan 2010	9	5	3
Feb 2010	6	5	2
Mar 2010	5	1	0
Apr 2010	5	5	2
May 2010	4	9	2
Jun 2010	12	4	5
Jul 2010	8	4	6
Aug 2010	20	11	2
Sep 2010	23	18	4
Oct 2010	11	14	2
Nov 2010	20	16	4
Dec 2010	10	10	0
Jan 2011	19	17	4
Feb 2011	10	19	2
Mar 2011	18	14	4
Apr 2011	10	8	2
May 2011	9	12	1
Jun 2011	17	7	1
Jul 2011	17	6	2
Aug 2011	20	3	0
Sep 2011	53	5	0
Oct 2011	35	5	2
Nov 2011	17	25	6
Dec 2011	7	28	6
Jan 2012	12	20	6
Feb 2012	14	30	5
Mar 2012	11	24	6
Apr 2012	7	17	7
May 2012	9	36	10
Jun 2012	13	31	5
Jul 2012	17	26	16
Aug 2012	13	25	13
Sep 2012	6	33	5
Oct 2012	10	33	11
Nov 2012	17	19	6
Dec 2012	14	16	4
Jan 2013	22	11	5
Feb 2013	10	23	5
Mar 2013	13	22	6
Apr 2013	14	18	7
May 2013	12	17	12
Jun 2013	5	10	2
Jul 2013	5	15	7
Aug 2013	15	7	5
Sep 2013	16	4	1
Oct 2013	17	10	5
Nov 2013	10	6	5
Dec 2013	11	5	6
Jan 2014	47	7	5
Feb 2014	14	17	3
Mar 2014	11	24	4
Apr 2014	9	13	8
May 2014	17	16	11
Jun 2014	10	18	3
Jul 2014	20	18	3
Aug 2014	20	18	15
Sep 2014	13	10	2
Oct 2014	7	14	4
Nov 2014	1	1	2
Dec 2014	12	6	6
Jan 2015	4	7	1
Feb 2015	17	7	2
Mar 2015	4	15	1
Apr 2015	3	5	3
May 2015	9	3	0
Jun 2015	13	6	4
Jul 2015	15	1	1
Aug 2015	9	1	0
Sep 2015	15	8	1
Oct 2015	8	9	2
Nov 2015	12	0	3
Dec 2015	4	2	0
Jan 2016	31	10	3
Feb 2016	8	5	3
Mar 2016	7	3	4
Apr 2016	13	1	10
May 2016	8	6	8
Jun 2016	10	3	2
Jul 2016	14	10	3
Aug 2016	13	11	0
Sep 2016	23	10	4
Oct 2016	13	9	4
Nov 2016	16	14	1
Dec 2016	9	11	1
Jan 2017	22	11	4
Feb 2017	4	4	2
Mar 2017	0	14	1
Apr 2017	2	12	3
May 2017	0	24	0
Jun 2017	0	10	0
Jul 2017	15	13	1
Aug 2017	25	16	2
Sep 2017	21	13	1
Oct 2017	35	27	2
Nov 2017	18	14	1
Dec 2017	22	16	1
Jan 2018	25	19	9
Feb 2018	20	12	1
Mar 2018	29	17	3
Apr 2018	33	28	0
May 2018	24	23	4
Jun 2018	31	31	3
Jul 2018	14	14	1
Aug 2018	14	12	1
Sep 2018	16	16	1
Oct 2018	14	14	3
Nov 2018	38	36	6
Dec 2018	12	12	3
Jan 2019	8	8	2
Feb 2019	16	12	3
Mar 2019	22	19	4
Apr 2019	19	19	7
May 2019	12	10	6
Jun 2019	9	7	9
Jul 2019	14	14	7
Aug 2019	12	8	7
Sep 2019	14	14	8
Oct 2019	20	14	6
Nov 2019	10	8	6
Dec 2019	18	14	4
Jan 2020	19	19	2
Feb 2020	11	9	4
Mar 2020	6	2	4
Apr 2020	5	5	2
May 2020	5	5	6
Jun 2020	17	15	5
Jul 2020	11	11	7
Aug 2020	10	9	13
Sep 2020	38	21	5
Oct 2020	16	12	4
Nov 2020	22	19	6
Dec 2020	24	21	10
Jan 2021	10	8	6
Feb 2021	14	12	4
Mar 2021	7	7	2
Apr 2021	7	5	3
May 2021	8	8	1
Jun 2021	8	9	9
Jul 2021	7	7	6
Aug 2021	8	8	3
Sep 2021	11	11	10
Oct 2021	13	11	18
Nov 2021	11	9	19
Dec 2021	17	13	7
Jan 2022	19	15	8
Feb 2022	14	10	11
Mar 2022	18	18	11
Apr 2022	21	21	11
May 2022	31	26	11
Jun 2022	26	22	9
Jul 2022	14	14	3
Aug 2022	43	43	5
Sep 2022	23	21	16
Oct 2022	34	31	12
Nov 2022	19	18	7
Dec 2022	14	11	5
Jan 2023	23	23	6
Feb 2023	50	48	5
Mar 2023	22	16	3
Apr 2023	11	8	5
May 2023	14	12	10
Jun 2023	10	8	2
Jul 2023	18	10	7
Aug 2023	21	18	7
Sep 2023	19	19	10
Oct 2023	19	13	10
Nov 2023	23	20	14
Dec 2023	36	7	0
Jan 2024	37	2	3
Feb 2024	35	2	1
Mar 2024	99	2	1
Total	4390	3690	1375

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