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Neuromyogenic properties of the internal anal sphincter: therapeutic rationale for anal fissures
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  • Published on: 4 January 2006
    Anal fissure treatment with Glyceryl trinitrate vs. Botulinum toxin
    • Dr prem chattoo, Gastroenterology and Hepatology
    • Other Contributors:
      • Dr Shamsul Alam Bhuiyan, Volunteer, NYU Downtown HOspital

    Dear Editor,

    We read this article with great interest. Treatment of anal fissure is really troublesome. Here the author puts emphasis on the Neuromyogenic properties of anal sphincter and treatment by topical glyceryl trinitrate, a nitric oxide donor, which decreases anal sphincter tone and improves anal mucosal blood flow and promotes the healing of anal fissures. Because of the easy application process glyceryl tri...

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    Conflict of Interest:
    None declared.