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Pancreatic tract
Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis

Authors

  • C D Johnson aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • A N Kingsnorth aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • C W Imrie aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • M J McMahon aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • J P Neoptolemos aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • C McKay aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • S K C Toh aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • P Skaife aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • P C Leeder aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • P Wilson aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • M Larvin aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  • L D Curtis aUniversity Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK, bDepartment of Surgery, Royal Liverpool University Hospital, 5th Floor, UCD Building, Daulby Street, Liverpool, L69 3GA, UK, cDepartment of Surgery, Royal Infirmary, Glasgow G31 2ER, UK, dAcademic Surgical Unit and Centre for Digestive Diseases, General Infirmary, St George Street, Leeds LA1 3EX, UK, eDepartment of Surgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK, fBritish Biotech, Watlington Road, Cowley, Oxford OX4 5LY, UK PubMed articlesGoogle scholar articles
  1. Mr C D Johnson, Reader in Surgery, Southampton General Hospital (Mail point 816), Southampton SO16 6YD, UK.c.d.johnson{at}soton.ac.uk
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Citation

Johnson CD, Kingsnorth AN, Imrie CW for the UK Acute Pancreatitis Study Group, et al
Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis
Gut 2001;48:62-69.

Publication history

  • Accepted June 22, 2000
  • First published January 1, 2001.
Online issue publication 
January 10, 2022

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British Society of Gastroenterology