Article Text

Download PDFPDF
Regression of gastric T cell lymphoma with eradication ofHelicobacter pylori


Helicobacter pylori is thought to be important in the pathogenesis of chronic active gastritis, peptic ulceration, gastric adenocarcinoma, and gastric B cell lymphoma of mucosa associated lymphoid tissue. The mechanism of evolution from chronic gastritis to monoclonal B cell proliferation is not known but is thought to be dependent on antigen specific T cells toH pylori and its products. Here, we report a case of gastric T cell lymphoma associated with chronicH pylori gastritis which regressed with eradication of the organism. This is the first report of a gastric T cell lymphoma regressing with H pylorieradication, and suggests a causal link between primary gastric T cell lymphoma and this organism.

  • Helicobacter pylori
  • T cell lymphoma
  • Abbreviations used in this paper

    mucosa associated lymphoid tissue
    polymerase chain reaction
    T cell receptor
    natural killer
  • Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.