Editor,—We read with interest the paper by Kronborg and colleagues (Gut2000:46:795–800)—a large multicentre study measuring faecal calprotectin levels in high risk populations for colorectal neoplasia.

The authors did not discuss their results in comparison with those of Roseth and colleagues1 or Kristinsson and colleagues2 who did the ground breaking work in this area and where calprotectin levels were shown to be far higher in patients with colonic polyps and cancer compared with normal controls (table 1).