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Editor,—We would like to thank Professor MacDonald for his interest in our work, and for his recent comment on our paper (
). However, we must take issue with a number of his comments.
With respect to the clinical implications of our study,1 we have not advocated treatment ofHelicobacter pylori infected patients with intestinal parasites for the purpose of inducing a shift in the Th1/Th2 immune response, a possibility raised by Professor MacDonald. As Professor MacDonald is well aware, this approach has been suggested for a number of chronic diseases such as inflammatory bowel disease. However, in the case of chronic H pylori infection, antibiotic therapy has proved effective and in our opinion is a much safer and more palatable approach for most patients.
We appreciate Professor MacDonald's careful analysis of our histopathological results. However, we are confused regarding his comments of “negative points” that were not sufficiently emphasised. …
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