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  • Variability in the severity of colonic disease in familial adenomatous polyposis results from differences in tumour initiation rather than progression and depends relatively little on patient age

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Cancer
Variability in the severity of colonic disease in familial adenomatous polyposis results from differences in tumour initiation rather than progression and depends relatively little on patient age

Authors

  • M D Crabtree aMolecular and Population Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK, bThe Academic Institute, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK, cAcademic Department of Histopathology, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK PubMed articlesGoogle scholar articles
  • I P M Tomlinson aMolecular and Population Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK, bThe Academic Institute, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK, cAcademic Department of Histopathology, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK PubMed articlesGoogle scholar articles
  • I C Talbot aMolecular and Population Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK, bThe Academic Institute, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK, cAcademic Department of Histopathology, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK PubMed articlesGoogle scholar articles
  • R K S Phillips aMolecular and Population Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK, bThe Academic Institute, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK, cAcademic Department of Histopathology, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK PubMed articlesGoogle scholar articles
  1. M D Crabtree, Molecular and Population Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.mitch_crabstix{at}lineone.net
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Citation

Crabtree MD, Tomlinson IPM, Talbot IC, et al
Variability in the severity of colonic disease in familial adenomatous polyposis results from differences in tumour initiation rather than progression and depends relatively little on patient age
Gut 2001;49:540-543.

Publication history

  • Accepted March 26, 2001
  • First published October 1, 2001.
Online issue publication 
January 10, 2022

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British Society of Gastroenterology