Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of Crohn's disease

J D Söderholm; G Olaison; K H Peterson; L E Franzén; T Lindmark; M Wirén; C Tagesson; R Sjödahl

doi:10.1136/gut.50.3.307

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Inflammation and inflammatory bowel disease

Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of Crohn's disease

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	Abstract	Full	Pdf
Feb 2002	137	150	76
Mar 2002	57	122	40
Apr 2002	10	64	21
May 2002	11	51	32
Jun 2002	5	26	13
Jul 2002	3	29	13
Aug 2002	2	29	16
Sep 2002	4	22	7
Oct 2002	2	32	13
Nov 2002	10	17	9
Dec 2002	2	31	20
Jan 2003	1	26	8
Feb 2003	7	45	20
Mar 2003	2	17	16
Apr 2003	5	26	19
May 2003	6	22	13
Jun 2003	1	15	13
Jul 2003	10	47	21
Aug 2003	23	30	6
Sep 2003	9	27	5
Oct 2003	17	48	18
Nov 2003	25	24	11
Dec 2003	15	26	12
Jan 2004	24	22	9
Feb 2004	16	18	10
Mar 2004	22	28	14
Apr 2004	22	22	2
May 2004	42	47	14
Jun 2004	48	66	12
Jul 2004	52	69	30
Aug 2004	27	37	27
Sep 2004	30	44	13
Oct 2004	16	41	24
Nov 2004	9	63	24
Dec 2004	18	70	24
Jan 2005	21	64	18
Feb 2005	6	38	12
Mar 2005	14	47	14
Apr 2005	17	48	25
May 2005	5	17	7
Jun 2005	13	44	43
Jul 2005	8	36	18
Aug 2005	16	26	15
Sep 2005	3	24	11
Oct 2005	22	28	13
Nov 2005	20	27	12
Dec 2005	14	31	11
Jan 2006	8	40	14
Feb 2006	8	26	14
Mar 2006	9	34	11
Apr 2006	7	24	7
May 2006	9	40	17
Jun 2006	10	18	12
Jul 2006	6	13	8
Aug 2006	5	27	22
Sep 2006	7	29	12
Oct 2006	15	32	18
Nov 2006	13	36	13
Dec 2006	11	18	6
Jan 2007	8	21	12
Feb 2007	14	36	25
Mar 2007	18	32	18
Apr 2007	30	10	9
May 2007	15	12	11
Jun 2007	14	6	3
Jul 2007	9	7	4
Aug 2007	16	10	3
Sep 2007	18	12	14
Oct 2007	22	6	7
Nov 2007	11	5	6
Dec 2007	6	5	4
Jan 2008	13	4	3
Feb 2008	14	10	9
Mar 2008	15	15	12
Apr 2008	30	15	4
May 2008	23	10	7
Jun 2008	21	13	9
Jul 2008	23	9	11
Aug 2008	19	1	5
Sep 2008	28	6	4
Oct 2008	16	10	7
Nov 2008	21	2	2
Dec 2008	15	7	6
Jan 2009	20	8	10
Feb 2009	19	8	4
Mar 2009	19	8	5
Apr 2009	13	5	1
May 2009	13	5	5
Jun 2009	24	3	6
Jul 2009	22	4	4
Aug 2009	45	4	8
Sep 2009	46	4	8
Oct 2009	56	8	3
Nov 2009	40	9	11
Dec 2009	36	2	6
Jan 2010	42	5	7
Feb 2010	45	1	3
Mar 2010	39	7	3
Apr 2010	27	14	7
May 2010	24	8	4
Jun 2010	20	5	6
Jul 2010	19	10	7
Aug 2010	37	14	2
Sep 2010	72	24	6
Oct 2010	82	22	4
Nov 2010	47	23	11
Dec 2010	43	15	2
Jan 2011	53	18	7
Feb 2011	51	7	0
Mar 2011	47	19	5
Apr 2011	50	27	7
May 2011	40	16	9
Jun 2011	39	2	4
Jul 2011	68	10	3
Aug 2011	60	18	7
Sep 2011	75	20	4
Oct 2011	74	36	10
Nov 2011	67	29	5
Dec 2011	30	67	14
Jan 2012	18	54	8
Feb 2012	26	39	4
Mar 2012	31	38	7
Apr 2012	14	54	9
May 2012	22	45	18
Jun 2012	23	48	18
Jul 2012	25	27	20
Aug 2012	14	35	19
Sep 2012	22	37	13
Oct 2012	28	79	18
Nov 2012	22	50	13
Dec 2012	17	17	8
Jan 2013	28	11	6
Feb 2013	30	22	16
Mar 2013	27	15	10
Apr 2013	31	20	14
May 2013	27	27	10
Jun 2013	12	10	4
Jul 2013	20	10	11
Aug 2013	21	8	5
Sep 2013	18	14	1
Oct 2013	37	25	6
Nov 2013	30	15	14
Dec 2013	82	68	4
Jan 2014	42	18	4
Feb 2014	37	10	3
Mar 2014	62	13	5
Apr 2014	81	17	11
May 2014	60	12	18
Jun 2014	51	23	6
Jul 2014	55	26	10
Aug 2014	58	21	5
Sep 2014	42	37	8
Oct 2014	35	52	7
Nov 2014	35	53	6
Dec 2014	23	31	3
Jan 2015	107	26	9
Feb 2015	164	9	4
Mar 2015	115	35	7
Apr 2015	59	35	4
May 2015	75	17	4
Jun 2015	48	17	5
Jul 2015	15	4	5
Aug 2015	16	6	3
Sep 2015	18	26	0
Oct 2015	7	8	2
Nov 2015	17	8	4
Dec 2015	13	11	2
Jan 2016	25	45	4
Feb 2016	38	22	7
Mar 2016	27	7	8
Apr 2016	23	7	5
May 2016	29	6	6
Jun 2016	23	16	8
Jul 2016	17	8	1
Aug 2016	22	7	2
Sep 2016	79	10	7
Oct 2016	41	16	6
Nov 2016	28	7	4
Dec 2016	28	8	4
Jan 2017	34	11	12
Feb 2017	6	9	5
Mar 2017	6	12	8
Apr 2017	7	26	8
May 2017	13	58	10
Jun 2017	8	26	3
Jul 2017	42	34	11
Aug 2017	37	28	12
Sep 2017	63	53	6
Oct 2017	53	39	0
Nov 2017	39	31	5
Dec 2017	18	14	3
Jan 2018	44	32	10
Feb 2018	39	21	4
Mar 2018	39	27	5
Apr 2018	39	30	11
May 2018	38	30	7
Jun 2018	41	33	8
Jul 2018	30	28	11
Aug 2018	55	41	16
Sep 2018	59	51	26
Oct 2018	50	44	11
Nov 2018	47	39	11
Dec 2018	42	38	9
Jan 2019	87	51	5
Feb 2019	40	33	16
Mar 2019	52	37	16
Apr 2019	30	20	22
May 2019	32	29	12
Jun 2019	30	30	14
Jul 2019	30	26	13
Aug 2019	34	26	16
Sep 2019	27	27	12
Oct 2019	39	31	16
Nov 2019	32	26	12
Dec 2019	35	30	5
Jan 2020	30	26	23
Feb 2020	19	19	35
Mar 2020	26	18	31
Apr 2020	37	29	13
May 2020	26	26	7
Jun 2020	42	33	16
Jul 2020	32	22	13
Aug 2020	31	17	12
Sep 2020	30	18	12
Oct 2020	56	45	21
Nov 2020	44	32	19
Dec 2020	60	32	31
Jan 2021	46	28	23
Feb 2021	49	29	12
Mar 2021	41	33	20
Apr 2021	55	45	14
May 2021	39	39	11
Jun 2021	25	25	13
Jul 2021	19	18	19
Aug 2021	13	12	12
Sep 2021	34	33	17
Oct 2021	43	41	46
Nov 2021	53	44	35
Dec 2021	32	25	11
Jan 2022	32	25	17
Feb 2022	22	20	14
Mar 2022	40	44	19
Apr 2022	50	41	22
May 2022	62	43	28
Jun 2022	53	40	14
Jul 2022	28	21	10
Aug 2022	41	39	11
Sep 2022	74	56	13
Oct 2022	62	47	20
Nov 2022	72	45	22
Dec 2022	55	42	14
Jan 2023	66	49	15
Feb 2023	70	53	13
Mar 2023	79	63	22
Apr 2023	43	33	20
May 2023	55	19	19
Jun 2023	45	30	13
Jul 2023	42	34	19
Aug 2023	35	26	20
Sep 2023	54	40	21
Oct 2023	82	65	16
Nov 2023	76	72	7
Dec 2023	401	100	4
Jan 2024	130	4	6
Feb 2024	168	6	4
Mar 2024	141	12	7
Total	9397	7290	3081

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