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Creutzfeldt-Jakob disease: implications for gastroenterology
  1. M G Bramble1,
  2. J W Ironside2
  1. 1Endoscopy Centre, James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW, UK
  2. 2CJD Surveillance Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
  1. Correspondence to:
    Professor MG Bramble, Endoscopy Centre, James Cook University Hospital, Marton Rd, Middlesbrough TS4 3BN, UK;


The current clinical views regarding variant Creutzfeldt-Jakob disease, and in particular transmission via endoscopy, of those representing both gastroenterology and the Spongiform Encephalopathy Advisory Committee are presented in an attempt to guide clinicians as to “best practice” given the current state of our knowledge.

  • Creutzfeldt-Jakob disease
  • endoscopy
  • vCJD, variant Creutzfeldt-Jakob disease
  • BSE, bovine spongiform encephalopathy
  • PrP, prion protein
  • CNS, central nervous system

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