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Novel targets for the control of secretory diarrhoea

Abstract

Secretory diarrhoea continues to be a major clinical problem worldwide. It is now recognised that the enteric nervous system plays an important role in the pathogenesis of enterotoxin mediated intestinal secretion, which has resulted in the identification of novel therapeutic targets for the treatment of acute watery diarrhoea.

  • intestinal secretion
  • enteric nervous system
  • enterotoxin
  • 5-hydroxytryptamine
  • enkephalinase inhibitor
  • CT, cholera toxin
  • ENS, enteric nervous system
  • LT, heat labile toxin
  • ST, heat stable toxin
  • VIP, vasoactive intestinal peptide

https://doi.org/10.1136/gut.50.suppl_3.iii15

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