Article Text

Download PDFPDF

Probiotics: a role in the treatment of intestinal infection and inflammation?
Free
  1. E Isolauri1,
  2. P V Kirjavainen2,
  3. S Salminen2
  1. 1Department of Paediatrics, University of Turku, Finland
  2. 2Department of Biochemistry and Food Chemistry, University of Turku
  1. Correspondence to:
    Dr E Isolauri, Department of Paediatrics, University of Turku, 20520 Turku, Finland;
    erika.isolauri{at}utu.fi

Abstract

Probiotic therapy is based on the concept of normal healthy microflora. The development of novel means of characterising the gut microflora, in particular those based on the different levels of conservation in the ribosomal RNA sequences of different genera, have opened up new angles on the role of the gut microflora in health and disease. Components of the human intestinal microflora or organisms entering the intestine may have harmful or beneficial effects on human health. Abundant evidence implies that specific strains selected from the healthy gut microflora exhibit powerful antipathogenic and anti-inflammatory capabilities, and are consequently involved with enhanced colonisation resistance in the intestine. Realisation of this has led to the introduction of novel modes of therapeutic and prophylactic intervention based on the consumption of mono and mixed cultures of beneficial live microorganisms as probiotics.

  • allergy
  • inflammation
  • microflora
  • probiotic
View Full Text

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.