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Review
Hepatitis C and HIV-1 coinfection
  1. A H Mohsen1,
  2. P Easterbrook1,
  3. C B Taylor2,
  4. S Norris3
  1. 1Academic Department of HIV/GU Medicine, King's College, University of London, London, UK
  2. 2Department of Sexual Health, King's College, University of London, London, UK
  3. 3Department of Hepatology, King's College, University of London, London, UK
  1. Correspondence to:
    Dr A H Mohsen, Academic Department of HIV/GU Medicine, Weston Education Centre, GKT School of Medicine, King's College, University of London, London SE5 9RJ, UK;
    Abdul.Mohsen{at}kcl.ac.uk

Abstract

Hepatitis C virus (HCV) has emerged as the cause of the second major epidemic of viral infection after human immunodeficiency virus (HIV) within the past two decades, and coinfection of HIV and HCV represents a growing problem for the future. This article reviews the current evidence on the epidemiology and clinical implications of an interaction between HIV-1 and HCV infection, and the current status of the management of patients with combined infection.

  • hepatitis C virus
  • retroviral therapy
  • hepatocellular carcinoma
  • human immunodeficiency virus
  • HCV, hepatitis C virus
  • HAART, highly active retroviral therapy
  • HCC, hepatocellular carcinoma
  • HIV-1, human immunodeficiency virus 1
  • AIDS, acquired immune deficiency syndrome
  • ALT, alanine aminotransferase
  • AST, aspartate aminotransferase

https://doi.org/10.1136/gut.51.4.601

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