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LETTER
Rectal proliferation and alcohol abuse
  1. K Filion1
  1. 1Department of Physiology, McGill University, Montreal, Quebec, Canada; kfilio@po-box.mcgill.ca
  1. Correspondence to:
    H K Seitz, Department of Medicine, Salem Medical Centre, Zeppelinstrasse 11–13, D-69121 Heidelberg, Germany;
    helmut_karl.seitz{at}urz.uni-heidelberg.de

https://doi.org/10.1136/gut.51.4.611-a

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    The study by Simanowski et al described some important features of rectal proliferation and alcohol abuse (Gut 2001;49:418–22). However, there are some methodological issues pertaining to the study which need clarification. Firstly, when performing multiple linear regression, it is essential to perform and report sample size and power estimate calculations. This omission, especially with a sample size of only 39 patients, leaves the reader wondering if this sample is sufficient in size and power to adequately support the conclusions drawn from their regression analysis. Furthermore, by not reporting a …

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