Safety and efficacy of low dose Escherichia coli enterotoxin adjuvant for urease based oral immunisation against Helicobacter pylori in healthy volunteers

S Banerjee; A Medina-Fatimi; R Nichols; D Tendler; M Michetti; J Simon; C P Kelly; T P Monath; P Michetti

doi:10.1136/gut.51.5.634

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Safety and efficacy of low dose Escherichia coli enterotoxin adjuvant for urease based oral immunisation against Helicobacter pylori in healthy volunteers

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	Abstract	Full	Pdf
Oct 2002	81	123	80
Nov 2002	43	62	38
Dec 2002	21	59	14
Jan 2003	12	25	11
Feb 2003	8	21	13
Mar 2003	6	24	13
Apr 2003	5	19	8
May 2003	7	15	16
Jun 2003	4	9	6
Jul 2003	40	53	4
Aug 2003	45	14	1
Sep 2003	47	9	4
Oct 2003	60	61	4
Nov 2003	52	14	6
Dec 2003	47	9	1
Jan 2004	130	17	1
Feb 2004	58	20	2
Mar 2004	39	18	6
Apr 2004	34	11	1
May 2004	53	40	1
Jun 2004	50	44	3
Jul 2004	53	53	5
Aug 2004	44	43	8
Sep 2004	43	44	7
Oct 2004	11	20	5
Nov 2004	13	18	6
Dec 2004	16	39	14
Jan 2005	25	39	4
Feb 2005	15	35	17
Mar 2005	14	13	2
Apr 2005	2	13	2
May 2005	6	18	8
Jun 2005	6	10	5
Jul 2005	5	9	4
Aug 2005	4	13	12
Sep 2005	7	10	2
Oct 2005	6	12	1
Nov 2005	9	10	7
Dec 2005	9	8	0
Jan 2006	3	4	1
Feb 2006	7	9	10
Mar 2006	3	11	8
Apr 2006	2	8	1
May 2006	3	7	4
Jun 2006	3	2	1
Jul 2006	4	5	2
Aug 2006	1	1	1
Sep 2006	2	8	2
Oct 2006	4	9	7
Nov 2006	1	9	8
Dec 2006	2	7	6
Jan 2007	4	10	10
Feb 2007	5	7	3
Mar 2007	3	3	5
Apr 2007	4	3	0
May 2007	6	6	2
Jun 2007	5	2	3
Jul 2007	5	3	4
Aug 2007	3	1	2
Sep 2007	3	1	1
Oct 2007	6	2	2
Nov 2007	8	3	0
Dec 2007	2	3	1
Jan 2008	12	1	2
Feb 2008	7	1	2
Mar 2008	13	6	0
Apr 2008	13	0	0
May 2008	9	4	5
Jun 2008	7	1	3
Jul 2008	13	4	3
Aug 2008	18	8	2
Sep 2008	54	2	1
Oct 2008	20	1	1
Nov 2008	14	2	0
Dec 2008	1	2	1
Jan 2009	7	3	3
Feb 2009	8	2	3
Mar 2009	19	0	1
Apr 2009	3	2	0
May 2009	3	3	0
Jun 2009	11	1	2
Jul 2009	14	1	1
Aug 2009	6	2	0
Sep 2009	10	1	3
Oct 2009	12	1	3
Nov 2009	12	1	1
Dec 2009	7	0	2
Jan 2010	1	0	1
Feb 2010	4	2	1
Mar 2010	5	3	2
Apr 2010	2	1	1
May 2010	2	0	0
Jun 2010	9	2	3
Jul 2010	5	2	4
Aug 2010	8	3	2
Sep 2010	5	4	1
Oct 2010	6	1	0
Nov 2010	9	3	1
Dec 2010	3	0	0
Jan 2011	9	3	2
Feb 2011	6	0	0
Mar 2011	4	0	0
Apr 2011	6	2	0
May 2011	5	2	2
Jun 2011	8	2	1
Jul 2011	3	1	6
Aug 2011	23	4	5
Sep 2011	12	2	1
Oct 2011	14	0	0
Nov 2011	14	1	3
Dec 2011	7	6	5
Jan 2012	19	5	3
Feb 2012	11	8	5
Mar 2012	7	4	4
Apr 2012	14	13	8
May 2012	9	7	4
Jun 2012	6	6	5
Jul 2012	8	13	7
Aug 2012	13	11	8
Sep 2012	10	6	8
Oct 2012	11	2	6
Nov 2012	18	5	4
Dec 2012	12	8	13
Jan 2013	15	7	4
Feb 2013	11	12	3
Mar 2013	15	10	3
Apr 2013	6	4	5
May 2013	2	7	3
Jun 2013	1	3	2
Jul 2013	5	3	3
Aug 2013	13	4	3
Sep 2013	3	4	0
Oct 2013	4	7	4
Nov 2013	9	4	3
Dec 2013	16	6	0
Jan 2014	8	4	5
Feb 2014	5	4	0
Mar 2014	7	3	7
Apr 2014	19	3	2
May 2014	11	2	5
Jun 2014	11	7	4
Jul 2014	14	7	2
Aug 2014	6	8	0
Sep 2014	4	0	1
Oct 2014	4	1	1
Nov 2014	5	2	4
Dec 2014	7	5	1
Jan 2015	4	1	0
Feb 2015	2	4	5
Mar 2015	12	9	3
Apr 2015	5	2	5
May 2015	8	2	1
Jun 2015	5	2	2
Jul 2015	8	1	1
Aug 2015	4	1	1
Sep 2015	8	7	1
Oct 2015	6	0	0
Nov 2015	6	1	2
Dec 2015	10	11	1
Jan 2016	10	5	2
Feb 2016	5	12	5
Mar 2016	9	1	7
Apr 2016	4	2	5
May 2016	15	1	4
Jun 2016	7	0	3
Jul 2016	7	13	1
Aug 2016	6	2	0
Sep 2016	7	2	2
Oct 2016	8	5	4
Nov 2016	8	2	3
Dec 2016	5	3	0
Jan 2017	6	3	6
Feb 2017	1	1	3
Mar 2017	0	8	3
Apr 2017	0	4	1
May 2017	0	23	3
Jun 2017	0	9	2
Jul 2017	10	10	2
Aug 2017	18	18	4
Sep 2017	11	11	14
Oct 2017	9	9	4
Nov 2017	9	9	6
Dec 2017	14	14	7
Jan 2018	52	52	25
Feb 2018	11	7	12
Mar 2018	11	11	3
Apr 2018	7	7	6
May 2018	5	5	2
Jun 2018	18	18	4
Jul 2018	11	11	5
Aug 2018	12	12	1
Sep 2018	8	8	9
Oct 2018	8	8	7
Nov 2018	20	20	10
Dec 2018	17	17	9
Jan 2019	30	30	1
Feb 2019	26	26	6
Mar 2019	17	18	6
Apr 2019	11	11	8
May 2019	32	32	7
Jun 2019	10	10	6
Jul 2019	14	12	11
Aug 2019	14	14	5
Sep 2019	12	12	14
Oct 2019	18	20	3
Nov 2019	27	27	11
Dec 2019	26	26	4
Jan 2020	18	18	4
Feb 2020	13	13	6
Mar 2020	20	20	6
Apr 2020	14	14	5
May 2020	24	24	5
Jun 2020	26	25	4
Jul 2020	17	17	4
Aug 2020	20	19	4
Sep 2020	28	27	3
Oct 2020	18	16	6
Nov 2020	21	21	8
Dec 2020	17	17	6
Jan 2021	17	14	8
Feb 2021	12	10	4
Mar 2021	13	12	4
Apr 2021	13	12	1
May 2021	18	18	10
Jun 2021	15	15	2
Jul 2021	8	8	12
Aug 2021	1	1	8
Sep 2021	6	5	11
Oct 2021	4	3	23
Nov 2021	2	1	15
Dec 2021	19	19	5
Jan 2022	10	11	8
Feb 2022	20	17	6
Mar 2022	10	8	4
Apr 2022	8	6	2
May 2022	26	24	19
Jun 2022	19	19	8
Jul 2022	10	10	1
Aug 2022	22	19	5
Sep 2022	21	21	16
Oct 2022	27	27	7
Nov 2022	6	6	4
Dec 2022	18	15	9
Jan 2023	8	8	3
Feb 2023	31	30	1
Mar 2023	14	11	3
Apr 2023	5	5	3
May 2023	9	7	10
Jun 2023	5	5	7
Jul 2023	5	5	12
Aug 2023	8	8	10
Sep 2023	7	7	4
Oct 2023	11	10	5
Nov 2023	16	16	1
Dec 2023	86	4	1
Jan 2024	34	2	0
Feb 2024	43	0	0
Mar 2024	59	6	2
Total	3587	2774	1249

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