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Fulminant Crohn’s colitis after allogeneic stem cell transplantation
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  • Published on:
    Crohn’s ileitis after liver transplantation from a living-related donor with Crohn’s disease
    • Konstantinos A. Papadakis, M.D.
    • Other Contributors:
      • Konstantinos A. Papadakis, Robin Matuk, Maria T. Abreu, Eric A. Vasiliauskas, Phillip R. Fleshner, Juan Lechago, Tram Tran, Fred F. Poordad, Paul Martin, John Vierling and Stephan R. Targan

    Dear Editor

    We read with interest the case described recently by Sonwalkar et al, of a patient who developed fulminant Crohn’s colitis after allogeneic stem cell transplantation (ASCT).[1] Although the donor had no known Crohn’s disease (CD) and did not carry the IBD3 or IBD5 haplotypes associated with CD, HLA class III mismatches at IBD3 and a CD-associated polymorphism of the 5'UTR of NOD2/CARD15 were presen...

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    Conflict of Interest:
    None declared.
  • Published on:
    Adoptive transfer of genetic susceptibility to Crohn's disease?

    Dear Editor

    We read with great interest the stimulating case report about fulminant Crohn’s colitis following allogenic stem cell transplantation by Sonwalkar and colleagues [1] and the respective editorial.[2] The authors and the editorialists hypothesize whether the colitis might be ascribed to the adoptive transfer of stem cells displaying genetic alterations which are associated with Crohn’s disease. However, the i...

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    Conflict of Interest:
    None declared.