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Five years of complete remission of gastric diffuse large B cell lymphoma after eradication of Helicobacter pylori infection
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  1. M M Alsolaiman1,
  2. G Bakis1,
  3. T Nazeer2,
  4. R P MacDermott1,
  5. J A Balint1
  1. 1Division of Gastroenterology, Albany Medical College, Albany, New York, USA
  2. 2Department of Medicine and Department of Pathology, Albany Medical College, Albany, New York, USA
  1. Correspondence to:
    Dr M Alsolaiman, Gastroenterology Division, 47 New Scotland Ave MC# 48, Albany, NY 12208, USA;
    modar9{at}hotmail.com

Abstract

Long term follow up data are not available for cases of diffuse large B cell gastric lymphoma treated by eradicating Helicobacter pylori alone. We present the case of an 82 year old man with diffuse large B cell lymphoma localised to the stomach which responded to H pylori eradication and which has not recurred after more than five years of close follow up. Our patient was not a candidate for other modalities of treatment. This case demonstrates that the option of treating H pylori infection as the initial trial of treatment for localised diffuse large B cell lymphoma is appropriate for consideration. If medical therapy using eradication of H pylori is used, it is essential that the patient undergoes close observation and repeated surveillance endoscopies.

  • B cell lymphoma
  • MALT lymphoma
  • Helicobacter pylori
  • MALT, mucosa associated lymphoid tissue
  • CT, computed tomography
  • EUS, endoscopic ultrasonography
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