For someone who attended one of the early proton transport meetings and who lived through the era of the discovery of histamine H₂ receptor antagonists and proton pump inhibitors, this volume makes fascinating reading. The elegant application of modern biochemical and molecular biology techniques has increased our knowledge of the intimate working of the proton pump in a remarkable manner. The book, written by key players in the field, describes, to use a hackneyed phrase, the cutting edge research that is being undertaken. The contributions are not restricted to proton transport but address the K⁺ and Cl⁻ channels in the parietal cell and the …