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- Published on: 18 April 2016
- Published on: 18 April 2016
- Published on: 18 April 2016
- Published on: 18 April 2016
- Published on: 18 April 2016Ghrelin and Helicobacter pyloriShow More
Dear Editor
We read with interest the article by Nwokolo et al reporting raised serum ghrelin levels following helicobacter pylori eradication.[1] There are some exceptions to the interpretation of the data that we would take.
The authors state that the increase in ghrelin levels seen in their study “lends support to the view that ghrelin could be involved in the long term regulation of body w...
Conflict of Interest:
None declared. - Published on: 18 April 2016Author's replyShow More
Dear Editor
Macadam et al. have rightly questioned whether our novel observation is merely epiphenomenal or of patho-physiological significance. Their “gut feeling” is that it is the former since the changes are “mild” and the ghrelin concentrations after Helicobacter pylori cure are no different from that seen in a non-obese western population. They also suggest that the “moderate” reduction of ghrelin...
Conflict of Interest:
None declared. - Published on: 18 April 2016Helicobacter Pylori, ghrelin and obesity.Show More
Dear Editor
Nwokolo et al. have demonstrated that following the eradication of Helicobacter pylori from asymptomatic patients, plasma ghrelin ‘ increases profoundly’.[1] Although we find these results interesting, we cannot agree with the conclusion that this may be causally linked to epidemiological observations of the rising incidence of obesity and oesophageal adenocarcinoma in Western populations....
Conflict of Interest:
None declared. - Published on: 18 April 2016Authors' replyShow More
Dear Editor
We would like to draw the attention of Murray et al.[1] to the objectives set out clearly in the introductory section of our paper.
Our study was not designed to address the question of whether ghrelin is involved in long-term regulation of body weight. Furthermore, the duration of the study was too short to see any change in BMI. More importantly, waist circumference would be a better...
Conflict of Interest:
None declared.