Responses

Download PDFPDF

Plasma ghrelin following cure of Helicobacter pylori
Free
Compose Response

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Statement of Competing Interests

PLEASE NOTE:

  • A rapid response is a moderated but not peer reviewed online response to a published article in a BMJ journal; it will not receive a DOI and will not be indexed unless it is also republished as a Letter, Correspondence or as other content. Find out more about rapid responses.
  • We intend to post all responses which are approved by the Editor, within 14 days (BMJ Journals) or 24 hours (The BMJ), however timeframes cannot be guaranteed. Responses must comply with our requirements and should contribute substantially to the topic, but it is at our absolute discretion whether we publish a response, and we reserve the right to edit or remove responses before and after publication and also republish some or all in other BMJ publications, including third party local editions in other countries and languages
  • Our requirements are stated in our rapid response terms and conditions and must be read. These include ensuring that: i) you do not include any illustrative content including tables and graphs, ii) you do not include any information that includes specifics about any patients,iii) you do not include any original data, unless it has already been published in a peer reviewed journal and you have included a reference, iv) your response is lawful, not defamatory, original and accurate, v) you declare any competing interests, vi) you understand that your name and other personal details set out in our rapid response terms and conditions will be published with any responses we publish and vii) you understand that once a response is published, we may continue to publish your response and/or edit or remove it in the future.
  • By submitting this rapid response you are agreeing to our terms and conditions for rapid responses and understand that your personal data will be processed in accordance with those terms and our privacy notice.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

Other responses

Jump to comment:

  • Published on:
    Authors' reply
    • Chuka U Nwokolo, Consultant Gastroenterologist
    • Other Contributors:
      • Harpal Randeva

    Dear Editor

    We would like to draw the attention of Murray et al.[1] to the objectives set out clearly in the introductory section of our paper.

    Our study was not designed to address the question of whether ghrelin is involved in long-term regulation of body weight. Furthermore, the duration of the study was too short to see any change in BMI. More importantly, waist circumference would be a better...

    Show More
    Conflict of Interest:
    None declared.
  • Published on:
    Ghrelin and Helicobacter pylori

    Dear Editor

    We read with interest the article by Nwokolo et al reporting raised serum ghrelin levels following helicobacter pylori eradication.[1] There are some exceptions to the interpretation of the data that we would take.

    The authors state that the increase in ghrelin levels seen in their study “lends support to the view that ghrelin could be involved in the long term regulation of body w...

    Show More
    Conflict of Interest:
    None declared.
  • Published on:
    Author's reply

    Dear Editor

    Macadam et al. have rightly questioned whether our novel observation is merely epiphenomenal or of patho-physiological significance. Their “gut feeling” is that it is the former since the changes are “mild” and the ghrelin concentrations after Helicobacter pylori cure are no different from that seen in a non-obese western population. They also suggest that the “moderate” reduction of ghrelin...

    Show More
    Conflict of Interest:
    None declared.
  • Published on:
    Helicobacter Pylori, ghrelin and obesity.
    • Robert C Macadam, Surgeon
    • Other Contributors:
      • Vishal Borse, Ibrahim Dodo, Stephen G. Pollard

    Dear Editor

    Nwokolo et al. have demonstrated that following the eradication of Helicobacter pylori from asymptomatic patients, plasma ghrelin ‘ increases profoundly’.[1] Although we find these results interesting, we cannot agree with the conclusion that this may be causally linked to epidemiological observations of the rising incidence of obesity and oesophageal adenocarcinoma in Western populations....

    Show More
    Conflict of Interest:
    None declared.