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New imaging techniques: promise or passe
  1. M B Wallace
  1. Division of Gastroenterolgy, Medical University of South Carolina, 96 Jonathon Lucas Boulevard, Charleston, SC 29425, USA;

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I read with great interest the article by Egger and colleagues (Gut 2003;52:18–23) evaluating laser induced fluorescence endoscopy (LIFE) and methylene blue (MB) directed biopsies for detection of dysplasia in Barrett’s oesophagus.

As the authors point out, there have been no fully published studies to date on this much talked about procedure. The authors found that LIFE and MB had limited accuracy, as did standard random biopsy. Although LIFE and MB detected a total of five cases of high grade dyplasia and 11 cases …

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