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Platelet count/spleen diameter ratio: proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis
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Other responses

  • Published on:
    Infallibility of a normal platelet count/spleen diameter ratio in ruling out oesophageal varices?

    Dear Editor

    I read with interest that an abnormal platelet count/spleen diameter ratio predicts the presence of oesophageal varices.[1] This otherwise excellent article contained a statistical error that I would like to bring to your attention.

    The authors report a 100% sensitivity of the diagnostic test (platelet count/spleen diameter ratio at a cutoff value of 909) in ruling out the diagnosis of eso...

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    Conflict of Interest:
    None declared.
  • Published on:
    Platelet count/Spleen diameter ratio as a predictor of oesophageal varices in alcoholic cirrhosis.

    Dear Editor

    We read with great interest the article by E Giannini et al. (Gut 2003;52:1200-1205) regarding platelet count/spleen diameter ratio, as a non invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis.[1] In patient with liver disease due to alcohol,platelet count is reduced due to the myelotoxic effect of alcohol.

    In your study only 16,55% (24/145...

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    Conflict of Interest:
    None declared.
  • Published on:
    Platelet count with or without spleen diameter? The case when accompanied is better than alone.

    Dear Editor

    We were pleased to receive the interesting comments that Thabut et al. made to our paper.[1] Indeed, their letter allows us to focus on some aspects of our study that we feel need to be further emphasised.

    As a general rule, a surrogate marker for a given variable (i.e., presence/absence of oesophageal varices) that already has a definite diagnostic means (i.e., endoscopy) should acco...

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    Conflict of Interest:
    None declared.
  • Published on:
    Prediction of oesophageal varices with platelet count/spleen diameter ratio or platelets alone ?

    Dear Editor

    We read with a great interest the article by Giannini et al. in a recent issue of Gut.[1]

    Since the incidence of chronic liver diseases is growing, we are convinced that the development of non-invasive predictive tools to identify cirrhotic patients with oesophageal varices is of major interest. Several markers have been studied, and among them platelet count is commonly reported to be a go...

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    Conflict of Interest:
    None declared.