Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs

T M MacDonald; S V Morant; J L Goldstein; T A Burke; D Pettitt

doi:10.1136/gut.52.9.1265

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Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs

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	Abstract	Full	Pdf
Aug 2003	188	433	264
Sep 2003	93	272	173
Oct 2003	59	208	74
Nov 2003	40	97	65
Dec 2003	41	95	62
Jan 2004	39	66	36
Feb 2004	39	67	42
Mar 2004	38	62	30
Apr 2004	21	57	30
May 2004	54	78	44
Jun 2004	60	117	24
Jul 2004	66	95	35
Aug 2004	65	83	13
Sep 2004	29	69	40
Oct 2004	30	120	114
Nov 2004	30	132	81
Dec 2004	16	79	50
Jan 2005	26	77	67
Feb 2005	27	52	25
Mar 2005	23	52	42
Apr 2005	11	62	34
May 2005	13	41	39
Jun 2005	31	41	30
Jul 2005	10	43	41
Aug 2005	14	40	33
Sep 2005	8	46	35
Oct 2005	14	48	33
Nov 2005	15	41	27
Dec 2005	13	25	23
Jan 2006	20	31	21
Feb 2006	16	35	22
Mar 2006	7	25	25
Apr 2006	10	19	19
May 2006	9	27	20
Jun 2006	9	18	18
Jul 2006	5	11	8
Aug 2006	11	23	18
Sep 2006	12	21	17
Oct 2006	27	27	17
Nov 2006	13	20	10
Dec 2006	6	12	9
Jan 2007	13	20	17
Feb 2007	28	20	16
Mar 2007	14	13	16
Apr 2007	16	4	5
May 2007	19	10	14
Jun 2007	8	8	9
Jul 2007	8	8	6
Aug 2007	21	6	7
Sep 2007	27	5	8
Oct 2007	13	5	10
Nov 2007	17	4	7
Dec 2007	15	6	3
Jan 2008	24	6	3
Feb 2008	13	4	3
Mar 2008	24	4	5
Apr 2008	19	3	5
May 2008	15	7	7
Jun 2008	17	6	11
Jul 2008	23	3	4
Aug 2008	23	2	4
Sep 2008	20	3	2
Oct 2008	16	7	8
Nov 2008	13	3	7
Dec 2008	9	2	5
Jan 2009	14	5	3
Feb 2009	22	4	6
Mar 2009	23	4	10
Apr 2009	25	2	5
May 2009	37	7	6
Jun 2009	18	1	3
Jul 2009	16	5	9
Aug 2009	16	1	3
Sep 2009	13	2	5
Oct 2009	14	7	4
Nov 2009	17	7	5
Dec 2009	5	0	2
Jan 2010	16	1	5
Feb 2010	13	2	7
Mar 2010	15	3	7
Apr 2010	9	2	4
May 2010	18	4	7
Jun 2010	14	2	8
Jul 2010	15	1	11
Aug 2010	13	2	3
Sep 2010	12	5	8
Oct 2010	9	4	1
Nov 2010	18	4	2
Dec 2010	1	0	0
Jan 2011	8	0	0
Feb 2011	8	4	3
Mar 2011	13	5	3
Apr 2011	11	4	6
May 2011	7	3	4
Jun 2011	9	3	2
Jul 2011	6	4	1
Aug 2011	8	0	2
Sep 2011	6	1	2
Oct 2011	13	5	4
Nov 2011	11	7	8
Dec 2011	10	7	3
Jan 2012	7	6	3
Feb 2012	12	5	4
Mar 2012	17	6	8
Apr 2012	19	3	12
May 2012	12	6	6
Jun 2012	17	18	16
Jul 2012	16	4	11
Aug 2012	17	4	11
Sep 2012	20	6	10
Oct 2012	16	8	12
Nov 2012	23	12	13
Dec 2012	17	13	6
Jan 2013	13	6	8
Feb 2013	17	18	3
Mar 2013	15	9	7
Apr 2013	20	11	10
May 2013	10	4	5
Jun 2013	2	5	1
Jul 2013	13	6	9
Aug 2013	12	8	1
Sep 2013	5	8	6
Oct 2013	16	3	5
Nov 2013	11	3	1
Dec 2013	9	6	9
Jan 2014	4	6	2
Feb 2014	9	4	3
Mar 2014	5	5	3
Apr 2014	16	6	9
May 2014	8	9	3
Jun 2014	12	3	6
Jul 2014	37	12	3
Aug 2014	10	7	5
Sep 2014	11	2	3
Oct 2014	6	3	7
Nov 2014	9	6	5
Dec 2014	12	4	3
Jan 2015	6	6	10
Feb 2015	10	3	15
Mar 2015	17	8	2
Apr 2015	11	6	5
May 2015	11	5	1
Jun 2015	10	12	4
Jul 2015	8	9	5
Aug 2015	6	6	5
Sep 2015	6	11	2
Oct 2015	10	4	1
Nov 2015	20	3	4
Dec 2015	12	9	2
Jan 2016	17	3	4
Feb 2016	17	2	3
Mar 2016	8	9	4
Apr 2016	13	7	7
May 2016	10	6	7
Jun 2016	15	7	9
Jul 2016	10	6	4
Aug 2016	8	5	4
Sep 2016	20	5	4
Oct 2016	19	12	8
Nov 2016	14	10	2
Dec 2016	5	10	1
Jan 2017	12	8	4
Feb 2017	7	7	1
Mar 2017	5	11	2
Apr 2017	1	27	4
May 2017	3	20	3
Jun 2017	3	14	2
Jul 2017	19	18	3
Aug 2017	21	21	2
Sep 2017	26	24	5
Oct 2017	33	27	2
Nov 2017	15	13	2
Dec 2017	24	22	1
Jan 2018	27	22	2
Feb 2018	17	15	2
Mar 2018	21	17	2
Apr 2018	30	27	12
May 2018	20	16	0
Jun 2018	27	25	4
Jul 2018	21	21	3
Aug 2018	17	17	2
Sep 2018	21	19	3
Oct 2018	19	13	2
Nov 2018	20	16	3
Dec 2018	19	17	5
Jan 2019	30	24	4
Feb 2019	11	12	2
Mar 2019	23	19	8
Apr 2019	34	29	7
May 2019	14	11	11
Jun 2019	12	13	11
Jul 2019	15	9	8
Aug 2019	19	13	9
Sep 2019	10	10	7
Oct 2019	16	14	9
Nov 2019	32	24	6
Dec 2019	21	13	8
Jan 2020	23	23	8
Feb 2020	16	16	4
Mar 2020	21	17	7
Apr 2020	14	14	12
May 2020	29	21	7
Jun 2020	30	18	5
Jul 2020	21	19	3
Aug 2020	11	7	4
Sep 2020	34	23	1
Oct 2020	25	18	8
Nov 2020	25	17	5
Dec 2020	17	14	7
Jan 2021	20	20	1
Feb 2021	10	8	9
Mar 2021	27	20	6
Apr 2021	14	14	6
May 2021	24	23	6
Jun 2021	7	7	3
Jul 2021	14	14	12
Aug 2021	10	10	6
Sep 2021	25	25	12
Oct 2021	19	17	20
Nov 2021	19	13	21
Dec 2021	14	12	5
Jan 2022	25	18	7
Feb 2022	22	17	7
Mar 2022	33	30	11
Apr 2022	35	29	7
May 2022	53	33	23
Jun 2022	35	32	8
Jul 2022	16	13	2
Aug 2022	25	24	3
Sep 2022	43	37	24
Oct 2022	35	30	9
Nov 2022	24	22	9
Dec 2022	14	12	3
Jan 2023	20	19	6
Feb 2023	44	39	3
Mar 2023	27	21	6
Apr 2023	14	12	11
May 2023	5	3	5
Jun 2023	32	18	3
Jul 2023	6	6	12
Aug 2023	11	7	6
Sep 2023	11	9	1
Oct 2023	29	25	8
Nov 2023	41	40	9
Dec 2023	78	12	0
Jan 2024	43	14	1
Feb 2024	37	5	0
Mar 2024	92	5	0
Total	4898	5203	3019

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