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A 54 year old woman presented with haematochezia of two weeks duration. She gave no history of straining at defecation or taking non-steroidal anti-inflammatory drugs. Physical examination was unremarkable. A colonoscopic image, showing a shallow longitudinal ulcer involving the anterolateral wall of the lower rectum and anal canal, is depicted in fig 1. Biopsies showed non-specific inflammation without the presence of fibromuscular obliteration. What further information should be obtained to make a definitive diagnosis? What is the most likely diagnosis?
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