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Helicobacter pylori infection and long term proton pump inhibitor therapy
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  • Published on:
    Helicobacter pylori and long term proton pump inhibitor therapy
    • Ernst J Kuipers, MD
    • Other Contributors:
      • Elly C. Klinkenberg-Knol, Anders Walan

    Dear Editor

    With interest did we read the editorial of Dr Ken McColl [1] pertaining to our publication in the January issue on cure of Helicobacter pylori infection in patients with reflux oesophagitis treated with omeprazole.

    We highly regard Dr McColl as an experienced clinical scientist and good friend. Nevertheless, we consider some of his editorial comments inaccurate and asking for a response....

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    Conflict of Interest:
    None declared.
  • Published on:
    Hypergastrinemia in patients infected with Helicobacter pylori, treated with proton pump inhibitors

    Dear Editor

    We read with interest the commentaries by McColl: Helicobacter pylori infection and long term proton pump inhibitor therapy.[1]

    It is remarkable that he did not mention gastrin at all although hypergastrinemia is a result of reduced gastric acidity [2] as well as Helicobacter pylori (HP) infection,[3] and that patients with HP infection treated with proton pump inhibitors (PPI) have additive...

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    Conflict of Interest:
    None declared.
  • Published on:
    H pylori infection and reflux oesophagitis
    • Jannis Kountouras, Associate Professor of Medicine, Gastroenterologist
    • Other Contributors:
      • Christos Zavos, Dimitrios Chatzopoulos

    Dear Editor

    We read with considerable interest Dr Kuipers' paper [1], that found no significant adverse impact on the severity of reflux disease or its control after two-year omeprazole therapy following H pylori (Hp) eradication, during which time gastritis largely healed. In the commentary by Dr McColl [2] it is stated that, although published data are conflicting, Schwizer et al. reported improvement i...

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    Conflict of Interest:
    None declared.