CDP571, a humanised monoclonal antibody to tumour necrosis factor α, for moderate to severe Crohn’s disease: a randomised, double blind, placebo controlled trial

W J Sandborn; B G Feagan; G Radford-Smith; A Kovacs; R Enns; A Innes; J Patel

doi:10.1136/gut.2003.035253

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Inflammatory bowel disease

CDP571, a humanised monoclonal antibody to tumour necrosis factor α, for moderate to severe Crohn’s disease: a randomised, double blind, placebo controlled trial

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	Abstract	Full	Pdf
Sep 2004	265	195	221
Oct 2004	107	158	110
Nov 2004	115	111	62
Dec 2004	52	64	26
Jan 2005	65	100	43
Feb 2005	51	84	35
Mar 2005	39	74	49
Apr 2005	11	54	19
May 2005	35	85	22
Jun 2005	17	60	18
Jul 2005	28	56	9
Aug 2005	28	43	17
Sep 2005	20	35	20
Oct 2005	20	57	32
Nov 2005	34	98	45
Dec 2005	18	47	25
Jan 2006	24	62	38
Feb 2006	22	54	31
Mar 2006	28	110	52
Apr 2006	27	60	34
May 2006	6	47	29
Jun 2006	23	41	21
Jul 2006	11	26	13
Aug 2006	17	30	28
Sep 2006	21	28	27
Oct 2006	29	38	29
Nov 2006	17	42	26
Dec 2006	22	19	15
Jan 2007	29	45	32
Feb 2007	24	37	28
Mar 2007	30	40	35
Apr 2007	38	9	24
May 2007	33	15	10
Jun 2007	31	9	9
Jul 2007	36	19	14
Aug 2007	38	11	11
Sep 2007	26	8	14
Oct 2007	27	12	9
Nov 2007	40	9	14
Dec 2007	30	7	11
Jan 2008	25	3	5
Feb 2008	46	13	14
Mar 2008	33	17	12
Apr 2008	31	18	13
May 2008	11	12	11
Jun 2008	18	6	6
Jul 2008	35	6	3
Aug 2008	26	6	3
Sep 2008	16	2	3
Oct 2008	21	5	5
Nov 2008	18	10	9
Dec 2008	19	5	7
Jan 2009	33	8	8
Feb 2009	23	9	7
Mar 2009	41	11	13
Apr 2009	24	6	6
May 2009	24	4	5
Jun 2009	23	1	5
Jul 2009	21	2	5
Aug 2009	20	1	1
Sep 2009	22	2	2
Oct 2009	42	4	3
Nov 2009	28	0	0
Dec 2009	60	4	5
Jan 2010	28	0	5
Feb 2010	29	2	9
Mar 2010	64	7	8
Apr 2010	33	8	9
May 2010	25	0	3
Jun 2010	19	1	7
Jul 2010	23	3	8
Aug 2010	30	2	2
Sep 2010	31	4	3
Oct 2010	30	1	2
Nov 2010	41	2	2
Dec 2010	50	6	2
Jan 2011	46	4	1
Feb 2011	27	16	2
Mar 2011	51	3	2
Apr 2011	29	2	4
May 2011	20	6	2
Jun 2011	31	0	0
Jul 2011	24	0	0
Aug 2011	24	0	0
Sep 2011	31	4	2
Oct 2011	20	6	4
Nov 2011	41	9	5
Dec 2011	43	24	7
Jan 2012	44	21	31
Feb 2012	27	14	9
Mar 2012	24	16	10
Apr 2012	21	11	5
May 2012	37	9	6
Jun 2012	27	11	5
Jul 2012	26	32	6
Aug 2012	25	23	7
Sep 2012	41	20	12
Oct 2012	32	19	9
Nov 2012	40	20	9
Dec 2012	31	23	10
Jan 2013	56	13	6
Feb 2013	41	25	9
Mar 2013	44	45	4
Apr 2013	47	39	10
May 2013	60	20	8
Jun 2013	32	13	3
Jul 2013	21	16	2
Aug 2013	28	12	5
Sep 2013	25	18	7
Oct 2013	51	11	4
Nov 2013	39	12	3
Dec 2013	28	16	7
Jan 2014	34	23	6
Feb 2014	25	13	5
Mar 2014	29	14	5
Apr 2014	37	20	9
May 2014	27	22	3
Jun 2014	16	25	4
Jul 2014	32	25	6
Aug 2014	19	23	7
Sep 2014	36	18	7
Oct 2014	28	13	7
Nov 2014	26	18	7
Dec 2014	6	8	2
Jan 2015	16	13	3
Feb 2015	26	18	14
Mar 2015	37	17	6
Apr 2015	17	16	2
May 2015	22	16	7
Jun 2015	19	13	6
Jul 2015	17	23	8
Aug 2015	28	17	9
Sep 2015	37	30	2
Oct 2015	34	29	9
Nov 2015	20	36	6
Dec 2015	33	35	4
Jan 2016	54	38	12
Feb 2016	49	38	5
Mar 2016	18	19	15
Apr 2016	14	16	14
May 2016	18	24	12
Jun 2016	20	17	4
Jul 2016	17	36	6
Aug 2016	15	14	1
Sep 2016	17	13	5
Oct 2016	32	20	8
Nov 2016	17	21	1
Dec 2016	19	10	1
Jan 2017	23	17	5
Feb 2017	3	11	4
Mar 2017	2	15	1
Apr 2017	0	17	1
May 2017	0	15	5
Jun 2017	3	27	3
Jul 2017	13	13	2
Aug 2017	9	7	1
Sep 2017	21	21	2
Oct 2017	17	15	1
Nov 2017	35	35	6
Dec 2017	27	25	2
Jan 2018	18	18	4
Feb 2018	13	11	5
Mar 2018	22	18	3
Apr 2018	45	45	0
May 2018	64	64	3
Jun 2018	37	37	1
Jul 2018	32	24	3
Aug 2018	19	19	4
Sep 2018	39	27	1
Oct 2018	18	16	3
Nov 2018	53	53	7
Dec 2018	37	37	1
Jan 2019	31	30	2
Feb 2019	39	36	5
Mar 2019	30	27	9
Apr 2019	24	16	12
May 2019	20	16	10
Jun 2019	13	13	1
Jul 2019	21	18	9
Aug 2019	11	11	3
Sep 2019	14	14	0
Oct 2019	19	18	8
Nov 2019	16	16	4
Dec 2019	14	14	5
Jan 2020	17	17	8
Feb 2020	24	23	2
Mar 2020	45	42	13
Apr 2020	4	4	4
May 2020	130	127	4
Jun 2020	18	16	7
Jul 2020	131	127	3
Aug 2020	7	7	9
Sep 2020	16	16	1
Oct 2020	19	16	3
Nov 2020	14	8	5
Dec 2020	14	10	2
Jan 2021	12	10	4
Feb 2021	21	21	4
Mar 2021	13	11	11
Apr 2021	9	7	4
May 2021	28	28	5
Jun 2021	5	5	4
Jul 2021	7	7	11
Aug 2021	15	15	10
Sep 2021	5	5	5
Oct 2021	7	7	23
Nov 2021	16	8	23
Dec 2021	16	16	7
Jan 2022	25	23	20
Feb 2022	19	19	8
Mar 2022	25	24	7
Apr 2022	14	14	5
May 2022	32	32	15
Jun 2022	21	21	2
Jul 2022	30	23	6
Aug 2022	30	30	6
Sep 2022	25	23	9
Oct 2022	28	21	8
Nov 2022	18	16	6
Dec 2022	29	29	4
Jan 2023	31	31	13
Feb 2023	46	47	0
Mar 2023	13	11	4
Apr 2023	5	5	5
May 2023	10	10	10
Jun 2023	7	7	1
Jul 2023	16	15	6
Aug 2023	10	8	6
Sep 2023	17	15	7
Oct 2023	18	17	6
Nov 2023	10	10	3
Dec 2023	105	6	3
Jan 2024	42	6	2
Feb 2024	32	4	0
Mar 2024	197	3	1
Apr 2024	60	0	2
May 2024	40	1	1
Jun 2024	39	3	1
Jul 2024	56	1	0
Aug 2024	54	1	1
Sep 2024	66	3	9
Oct 2024	58	1	0
Nov 2024	88	4	1
Total	7453	5427	2448

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