Article Text
Letter
Risk of duodenal cancer in patients with familial adenomatous polyposis
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Bülow et al published results of a prospective multicentre study on analysis of the natural history of duodenal adenomas in familial adenomatous polyposis (FAP) (Gut 2004;53:381–6).
A total of 368 patients were examined over a mean period of 7.6 years (range 0.5–10.4). They showed significant progression of Spigelman stage over time (p<0.0001). At the end of the study, the incidence of Spigelman stage IV was 7.0%. These results are lower than those …