Responses

Download PDFPDF

A genetic test which can be used to diagnose adult-type hypolactasia in children
Free
Compose Response

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Statement of Competing Interests

PLEASE NOTE:

  • A rapid response is a moderated but not peer reviewed online response to a published article in a BMJ journal; it will not receive a DOI and will not be indexed unless it is also republished as a Letter, Correspondence or as other content. Find out more about rapid responses.
  • We intend to post all responses which are approved by the Editor, within 14 days (BMJ Journals) or 24 hours (The BMJ), however timeframes cannot be guaranteed. Responses must comply with our requirements and should contribute substantially to the topic, but it is at our absolute discretion whether we publish a response, and we reserve the right to edit or remove responses before and after publication and also republish some or all in other BMJ publications, including third party local editions in other countries and languages
  • Our requirements are stated in our rapid response terms and conditions and must be read. These include ensuring that: i) you do not include any illustrative content including tables and graphs, ii) you do not include any information that includes specifics about any patients,iii) you do not include any original data, unless it has already been published in a peer reviewed journal and you have included a reference, iv) your response is lawful, not defamatory, original and accurate, v) you declare any competing interests, vi) you understand that your name and other personal details set out in our rapid response terms and conditions will be published with any responses we publish and vii) you understand that once a response is published, we may continue to publish your response and/or edit or remove it in the future.
  • By submitting this rapid response you are agreeing to our terms and conditions for rapid responses and understand that your personal data will be processed in accordance with those terms and our privacy notice.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

Other responses

Jump to comment:

  • Published on:
    Statistical points arising from Author’s Reply

    Dear Editor,

    I write as the statistician on the paper by Mulcare and collaborators [1] which was criticised by Drs Kolho and Järvelä in their "Author's Reply" eLetter to Gut Online. I wish to correct two assertions made by Drs Kolho and Järvelä. The first is their claim that our statistical procedure “contains a risk for wrong conclusions” because “adult-type hypolactasia is difficult to assess due to inaccurate d...

    Show More
    Conflict of Interest:
    None declared.
  • Published on:
    Author's reply

    Dear Editor,

    Dr Swallow raises a question about another DNA-variant underlying adult- type hypolactasia in sub-Saharan populations and does not recommend the analysis of the C/T-13910 variant as a genetic test in African and non-Northern European populations. Although the studies performed by us [1-3] and others [4-5] do not support the existence of another variant, we agree with Dr. Swallow that well-conducted s...

    Show More
    Conflict of Interest:
    None declared.
  • Published on:
    DNA test for hypolactasia premature.

    Dear Editor,

    I write in response to the recently published article by Rasinperä and colleagues [1] in which a DNA test is proposed for ‘adult type hypolactasia’.

    The ability to digest the milk sugar lactose as an adult (lactase persistence) is a variable genetic trait in human populations, lactase persistence being the most frequent phenotype in northern Europe, while lactase non-persistence or ‘adult...

    Show More
    Conflict of Interest:
    None declared.