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We read the article by Rutter et al (Gut 2004;53:256–60) with great interest. They demonstrated that a dye spraying method with indigo carmine successfully detected dysplastic lesions in surveillance colonoscopy for ulcerative colitis (UC), and proved by back to back colonoscopy that such a method is effective. Since 1979, we have carried out a surveillance colonoscopy programme for UC associated cancer in which we successfully detected colitic cancer at an early stage.1 We have routinely used the dye spraying method with indigo carmine, which enables us to recognise subtle mucosal irregularities. Furthermore, we recently introduced magnifying colonoscopy and pit pattern diagnosis for surveillance colonoscopy for UC.2
We agree with Rutter et al that dye spraying can visualise flat dysplastic lesions. …