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  • Prognostic significance of microsatellite instability determined by immunohistochemical staining of MSH2 and MLH1 in sporadic T3N0M0 colon cancer

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Colon cancer
Prognostic significance of microsatellite instability determined by immunohistochemical staining of MSH2 and MLH1 in sporadic T3N0M0 colon cancer
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  • Published on: 18 April 2016
    Microsatellite instability and chemotherapy
    • Toshiaki Watanabe, Medical Doctor
    • Other Contributors:
      • Takamitsu Kanazawa, Tomohiro Tada, Yoshihiro Kazama, Keisuke Hata, Soichiro Ishihara, Hirokazu Nagawa.

    Dear Editor

    The article by Parc et al. revealed that microsatellite instability (MSI) determined by immunohistochemical staining of MSH2 and MLH1 is an independent predictive factor of good prognosis in sporadic T3N0M0 colon cancer.[1]

    They successfully showed that patients with MSI tumors exhibited significantly better survival than those with microsatellite stable (MSS) tumors. Furthermore, they...

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    Conflict of Interest:
    None declared.