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Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis
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    Probiotics in IBD: mucosal and systemic routes of administration may promote similar effects.
    • Benoit Foligne, Researcher
    • Other Contributors:
      • Benoit Foligne, Corinne Grangette, and Bruno Pot.

    Dear Editor

    We read with considerable interest the paper by Sheil et al.[1] who reported the successful application of the subcutaneous route for the probiotic attenuation of colitis.

    We agree with the corresponding commentary of Ghosh et al.[2] regarding the need to study mechanisms underlying probiotic interactions. Recently, we further standardized a method to compare the anti-inflammatory pot...

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    Conflict of Interest:
    None declared.