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Dysbiosis as a prerequisite for IBD
  1. C P Tamboli1,
  2. C Neut2,
  3. P Desreumaux3,
  4. J F Colombel3
  1. 1Division of Gastroenterology, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA
  2. 2Laboratoire de Bacteriologie, Faculté de Pharmacie, Lille, France, and INSERM EPI0114, CHU Lille, France
  3. 3Service d’Hepatogastroenterologie, Hopital Huriez, and INSERM EPI0114, CHU Lille, France
  1. Correspondence to:
    Dr C P Tamboli
    Division of Gastroenterology, University of Iowa Hospitals and Clinics, 200 Haskins Dr, Iowa City 52242, USA; cyrus-tamboliuiowa.edu

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We thank Dr Szilagyi for his very interesting comments in his letter regarding dysbiosis in inflammatory bowel disease (IBD).1

The main question remains as to why beneficial bacteria such as bifidobacteria might be lacking in IBD (Gut 2004;53:1–4). Dr Szilagyi describes an interesting hypothesis of colonic prebiotic deficiency as a possible mechanism for dysbiosis. A suggestion …

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