The advent of recombinant peptide technology offers the potential to use one or several peptides to treat a variety of gastrointestinal conditions. However, although cell culture and animal models have shown proof of concept, we are still at a relatively early stage in translating their use to standard clinical practice. Similarly, peptide and non-peptide antagonists of growth factor receptors show great potential as novel antichemotherapy agents. However, their actual place in clinical practice has yet to be established.
- EGF, epidermal growth factor
- EGFR, epidermal growth factor receptor
- GLP-2, glucagon-like peptide 2
- TGF-β, transforming growth factor β
- GnRH, gonadotrophin releasing hormone
- TKI, tyrosine kinase inhibitor
- epidermal growth factor
- receptor blockade
- gastrointestinal cancer
- growth factor receptors
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