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Genetic association between EPHX1 and Crohn’s disease: population stratification, genotyping error, or random chance?
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  • Published on:
    No genetic association between EPHX1 and Crohn’s disease.
    • Wilbert HM Peters, Biochemist
    • Other Contributors:
      • Elise MJ van der Logt, Rene HM te Morsche, Hennie MJ Roelofs, Dirk J de Jong, Ton HJ Naber
    Dear Editor

    In a case-control study on the associations between functional genetic polymorphisms in biotransformation enzymes and Crohn’s disease, we found a strong association of the Tyr113His (348T>C) polymorphism in exon 3 of the microsomal epoxide hydrolase (EPHX1) gene and Crohn’s disease.[1] The three referees all agreed that the study was interesting and should be published so that other groups can attempt to...

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    Conflict of Interest:
    None declared.